BP

GO:0006661

phosphatidylinositol biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.

TAS

BP

GO:0032288

myelin assembly

The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.

IEA

BP

GO:0034504

protein localization to nucleus

A process in which a protein is transported to, or maintained in, a location within the nucleus.

IMP

BP

GO:0035556

intracellular signal transduction

The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

IEA

BP

GO:0036092

phosphatidylinositol-3-phosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.

IEA

BP

GO:0042147

retrograde transport, endosome to Golgi

The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.

IMP

BP

GO:0046854

phosphatidylinositol phosphorylation

The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol.

IEA

BP

GO:1904562

phosphatidylinositol 5-phosphate metabolic process

The chemical reactions and pathways involving phosphatidylinositol 5-phosphate.

IC

BP

GO:2000785

regulation of autophagosome assembly

Any process that modulates the frequency, rate or extent of autophagosome assembly.

IMP

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IEA

CC

GO:0005911

cell-cell junction

A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.

IEA

CC

GO:0010008

endosome membrane

The lipid bilayer surrounding an endosome.

IDA

CC

GO:0012506

vesicle membrane

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

IEA

CC

GO:0031410

cytoplasmic vesicle

A vesicle found in the cytoplasm of a cell.

IEA

CC

GO:0031901

early endosome membrane

The lipid bilayer surrounding an early endosome.

IDA|TAS

CC

GO:0031902

late endosome membrane

The lipid bilayer surrounding a late endosome.

TAS

CC

GO:0045121

membrane raft

Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.

IDA

CC

GO:0048471

perinuclear region of cytoplasm

Cytoplasm situated near, or occurring around, the nucleus.

IEA

MF

GO:0000285

1-phosphatidylinositol-3-phosphate 5-kinase activity

Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H(+).

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0005524

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

IEA

MF

GO:0008270

zinc ion binding

Interacting selectively and non-covalently with zinc (Zn) ions.

IEA

MF

GO:0016308

1-phosphatidylinositol-4-phosphate 5-kinase activity

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+).

TAS

MF

GO:0043813

phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate.

TAS