BP

GO:0006382

adenosine to inosine editing

The conversion of an adenosine residue to inosine in an RNA molecule by deamination.

IMP

BP

GO:0006402

mRNA catabolic process

The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.

IDA

BP

GO:0006508

proteolysis

The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

IEA

BP

GO:0008284

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

IMP

BP

GO:0016077

snoRNA catabolic process

The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins.

IDA

BP

GO:0016311

dephosphorylation

The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.

IEA

BP

GO:0034656

nucleobase-containing small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.

TAS

BP

GO:0035863

dITP catabolic process

The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.

ISS

BP

GO:0046709

IDP catabolic process

The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.

IDA

BP

GO:0090068

positive regulation of cell cycle process

Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

IMP

BP

GO:1901639

XDP catabolic process

The chemical reactions and pathways resulting in the breakdown of XDP.

IDA

BP

GO:2000233

negative regulation of rRNA processing

Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.

ISS

BP

GO:2000781

positive regulation of double-strand break repair

Any process that activates or increases the frequency, rate or extent of double-strand break repair.

IMP

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

TAS

CC

GO:0005730

nucleolus

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

IDA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

IDA

MF

GO:0003729

mRNA binding

Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.

IDA

MF

GO:0005525

GTP binding

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

IDA

MF

GO:0008235

metalloexopeptidase activity

Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

IDA

MF

GO:0030145

manganese ion binding

Interacting selectively and non-covalently with manganese (Mn) ions.

IDA

MF

GO:0030515

snoRNA binding

Interacting selectively and non-covalently with small nucleolar RNA.

IDA

MF

GO:0035870

dITP diphosphatase activity

Catalysis of the reaction: dITP + H2O = dIMP + diphosphate.

ISS

MF

GO:0042803

protein homodimerization activity

Interacting selectively and non-covalently with an identical protein to form a homodimer.

IDA

MF

GO:0050072

m7G(5')pppN diphosphatase activity

Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide.

IDA

MF

GO:0050897

cobalt ion binding

Interacting selectively and non-covalently with a cobalt (Co) ion.

IDA

MF

GO:0090450

inosine-diphosphatase activity

Catalysis of the reaction: IDP + H2O = IMP + phosphate.

EXP

MF

GO:0097383

dIDP diphosphatase activity

Catalysis of the reaction: dIDP + H2O = dIMP + phosphate.

EXP

MF

GO:0098519

nucleotide phosphatase activity, acting on free nucleotides

Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate.

IDA

MF

GO:1901640

XTP binding

Interacting selectively and non-covalently with XTP.

IDA

MF

GO:1901641

ITP binding

Interacting selectively and non-covalently with ITP.

IDA