Protein Description

Gene Symbol MBOAT2
Entrez ID 129642
Uniprot ID Q6ZWT7
Description membrane bound O-acyltransferase domain containing 2
Chromosomal Location chr2: 8,852,690-9,003,813
Ontology GO ID GO Term Definition Evidence

BP

GO:0008654

phospholipid biosynthetic process

The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.

IEA

BP

GO:0036151

phosphatidylcholine acyl-chain remodeling

Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.

TAS

BP

GO:0036152

phosphatidylethanolamine acyl-chain remodeling

Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.

TAS

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

TAS

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

MF

GO:0003841

1-acylglycerol-3-phosphate O-acyltransferase activity

Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.

TAS

MF

GO:0047144

2-acylglycerol-3-phosphate O-acyltransferase activity

Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.

TAS

Domain ID Description

IPR004299

Membrane bound O-acyl transferase, MBOAT

Pathway ID Pathway Term Pathway Source

hsa00561

Glycerolipid metabolism

KEGG

hsa00564

Glycerophospholipid metabolism

KEGG

hsa01100

Metabolic pathways

KEGG

No diseases found.

Tissue Cell Type

cerebral cortex

neuronal cells

colon

glandular cells

duodenum

glandular cells

endometrium

cells in endometrial stroma

endometrium

glandular cells

epididymis

glandular cells

gallbladder

glandular cells

lymph node

non-germinal center cells

pancreas

exocrine glandular cells

parathyroid gland

glandular cells

placenta

decidual cells

placenta

trophoblastic cells

prostate

glandular cells

rectum

glandular cells

salivary gland

glandular cells

seminal vesicle

glandular cells

small intestine

glandular cells

stomach

glandular cells

testis

Leydig cells

tonsil

non-germinal center cells

No databases found.

Pubmed ID Author Year Title

15308691

Jansen et al.

2004

Abnormal Gene Expression Profiles in Human Ovaries from Polycystic Ovary Syndrome Patients

Gene Symbol Entrez ID Uniprot ID Score

TCTN3

26123

Q6NUS6

0.49

TCTN2

79867

Q96GX1

0.49