| Gene Symbol | MBOAT2 |
| Entrez ID | 129642 |
| Uniprot ID | Q6ZWT7 |
| Description | membrane bound O-acyltransferase domain containing 2 |
| Chromosomal Location | chr2: 8,852,690-9,003,813 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0008654 |
phospholipid biosynthetic process |
The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester. |
IEA |
|
BP |
GO:0036151 |
phosphatidylcholine acyl-chain remodeling |
Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains. |
TAS |
|
BP |
GO:0036152 |
phosphatidylethanolamine acyl-chain remodeling |
Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains. |
TAS |
|
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
TAS |
|
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
|
MF |
GO:0003841 |
1-acylglycerol-3-phosphate O-acyltransferase activity |
Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate. |
TAS |
|
MF |
GO:0047144 |
2-acylglycerol-3-phosphate O-acyltransferase activity |
Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA. |
TAS |
| Domain ID | Description |
|---|---|
|
IPR004299 |
Membrane bound O-acyl transferase, MBOAT |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa00561 |
Glycerolipid metabolism |
KEGG |
|
hsa00564 |
Glycerophospholipid metabolism |
KEGG |
|
hsa01100 |
Metabolic pathways |
KEGG |
| Tissue | Cell Type |
|---|---|
|
cerebral cortex |
neuronal cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
gallbladder |
glandular cells |
|
lymph node |
non-germinal center cells |
|
pancreas |
exocrine glandular cells |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
small intestine |
glandular cells |
|
stomach |
glandular cells |
|
testis |
Leydig cells |
|
tonsil |
non-germinal center cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
15308691 |
Jansen et al. |
2004 |
Abnormal Gene Expression Profiles in Human Ovaries from Polycystic Ovary Syndrome Patients |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
TCTN3 |
26123 |
Q6NUS6 |
0.49 |
|
TCTN2 |
79867 |
Q96GX1 |
0.49 |