Gene Symbol | MBOAT2 |
Entrez ID | 129642 |
Uniprot ID | Q6ZWT7 |
Description | membrane bound O-acyltransferase domain containing 2 |
Chromosomal Location | chr2: 8,852,690-9,003,813 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0008654 |
phospholipid biosynthetic process |
The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester. |
IEA |
BP |
GO:0036151 |
phosphatidylcholine acyl-chain remodeling |
Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains. |
TAS |
BP |
GO:0036152 |
phosphatidylethanolamine acyl-chain remodeling |
Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains. |
TAS |
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
TAS |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
MF |
GO:0003841 |
1-acylglycerol-3-phosphate O-acyltransferase activity |
Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate. |
TAS |
MF |
GO:0047144 |
2-acylglycerol-3-phosphate O-acyltransferase activity |
Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA. |
TAS |
Domain ID | Description |
---|---|
IPR004299 |
Membrane bound O-acyl transferase, MBOAT |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00561 |
Glycerolipid metabolism |
KEGG |
hsa00564 |
Glycerophospholipid metabolism |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
Tissue | Cell Type |
---|---|
cerebral cortex |
neuronal cells |
colon |
glandular cells |
duodenum |
glandular cells |
endometrium |
cells in endometrial stroma |
endometrium |
glandular cells |
epididymis |
glandular cells |
gallbladder |
glandular cells |
lymph node |
non-germinal center cells |
pancreas |
exocrine glandular cells |
parathyroid gland |
glandular cells |
placenta |
decidual cells |
placenta |
trophoblastic cells |
prostate |
glandular cells |
rectum |
glandular cells |
salivary gland |
glandular cells |
seminal vesicle |
glandular cells |
small intestine |
glandular cells |
stomach |
glandular cells |
testis |
Leydig cells |
tonsil |
non-germinal center cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
15308691 |
Jansen et al. |
2004 |
Abnormal Gene Expression Profiles in Human Ovaries from Polycystic Ovary Syndrome Patients |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
TCTN3 |
26123 |
Q6NUS6 |
0.49 |
TCTN2 |
79867 |
Q96GX1 |
0.49 |