| Gene Symbol | MBOAT2 |
| Entrez ID | 129642 |
| Uniprot ID | Q6ZWT7 |
| Description | membrane bound O-acyltransferase domain containing 2 |
| Chromosomal Location | chr2: 8,852,690-9,003,813 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0008654 | phospholipid biosynthetic process |
The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester. | IEA |
BP | GO:0036151 | phosphatidylcholine acyl-chain remodeling |
Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains. | TAS |
BP | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling |
Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains. | TAS |
CC | GO:0005789 | endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. | TAS |
CC | GO:0016021 | integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | IEA |
MF | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity |
Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate. | TAS |
MF | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity |
Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA. | TAS |
| Domain ID | Description |
|---|---|
IPR004299 | Membrane bound O-acyl transferase, MBOAT |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
hsa00561 | Glycerolipid metabolism | KEGG |
hsa00564 | Glycerophospholipid metabolism | KEGG |
hsa01100 | Metabolic pathways | KEGG |
| Tissue | Cell Type |
|---|---|
cerebral cortex | neuronal cells |
colon | glandular cells |
duodenum | glandular cells |
endometrium | cells in endometrial stroma |
endometrium | glandular cells |
epididymis | glandular cells |
gallbladder | glandular cells |
lymph node | non-germinal center cells |
pancreas | exocrine glandular cells |
parathyroid gland | glandular cells |
placenta | decidual cells |
placenta | trophoblastic cells |
prostate | glandular cells |
rectum | glandular cells |
salivary gland | glandular cells |
seminal vesicle | glandular cells |
small intestine | glandular cells |
stomach | glandular cells |
testis | Leydig cells |
tonsil | non-germinal center cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
15308691 | Jansen et al. | 2004 | Abnormal Gene Expression Profiles in Human Ovaries from Polycystic Ovary Syndrome Patients |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
TCTN3 | 26123 | Q6NUS6 | 0.49 |
TCTN2 | 79867 | Q96GX1 | 0.49 |