Gene Symbol | FOPNL |
Entrez ID | 123811 |
Uniprot ID | Q96NB1 |
Description | FGFR1OP N-terminal like |
Chromosomal Location | chr16: 15,865,720-15,888,625 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0034453 |
microtubule anchoring |
Any process in which a microtubule is maintained in a specific location in a cell. |
IEA |
BP |
GO:0042384 |
cilium assembly |
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. |
IMP |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
CC |
GO:0005813 |
centrosome |
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. |
IDA |
CC |
GO:0031514 |
motile cilium |
A cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface. Motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues. Motile cilia may also function as sensory organelles. |
ISS |
CC |
GO:0034451 |
centriolar satellite |
A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome. |
IDA |
CC |
GO:0036064 |
ciliary basal body |
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport. |
ISS |
Domain ID | Description |
---|---|
IPR006594 |
LIS1 homology motif |
IPR018993 |
FGFR1 oncogene partner (FOP), N-terminal dimerisation domain |
Tissue | Cell Type |
---|---|
bronchus |
respiratory epithelial cells |
esophagus |
squamous epithelial cells |
fallopian tube |
glandular cells |
heart muscle |
myocytes |
nasopharynx |
respiratory epithelial cells |
skeletal muscle |
myocytes |
skin |
keratinocytes |
smooth muscle |
smooth muscle cells |
soft tissue |
chondrocytes |
tonsil |
squamous epithelial cells |
vagina |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
17148555 |
Wood et al. |
2007 |
Molecular Abnormalities in Oocytes from Women with Polycystic Ovary Syndrome Revealed by Microarray Analysis |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
FOPNL |
123811 |
Q96NB1 |
0.63 |
PCM1 |
5108 |
Q15154 |
0.75 |
KIAA0753 |
9851 |
Q2KHM9 |
0.49 |
CEP162 |
22832 |
Q5TB80 |
0.49 |
CEP290 |
80184 |
O15078 |
0.49 |
CEP63 |
80254 |
Q96MT8 |
0.49 |
CEP128 |
145508 |
Q6ZU80 |
0.49 |
ELAVL1 |
1994 |
Q15717 |
0.63 |
CSNK1E |
1454 |
P49674 |
0.72 |
DYNLL1 |
8655 |
P63167 |
0.72 |
FGFR1OP |
11116 |
O95684 |
0.72 |
SLAIN2 |
57606 |
Q9P270 |
0.72 |
CCDC14 |
64770 |
Q49A88 |
0.72 |
OFD1 |
8481 |
O75665 |
0.82 |
CEP135 |
9662 |
Q66GS9 |
0.82 |