Gene Symbol | ADSSL1 |
Entrez ID | 122622 |
Uniprot ID | Q8N142 |
Description | adenylosuccinate synthase like 1 |
Chromosomal Location | chr14: 104,724,186-104,747,325 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0002376 |
immune system process |
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. |
NAS |
BP |
GO:0006167 |
AMP biosynthetic process |
The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate. |
IDA |
BP |
GO:0006531 |
aspartate metabolic process |
The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. |
IEA |
BP |
GO:0006541 |
glutamine metabolic process |
The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. |
IEA |
BP |
GO:0009168 |
purine ribonucleoside monophosphate biosynthetic process |
The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar. |
TAS |
BP |
GO:0014850 |
response to muscle activity |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. |
IEA |
BP |
GO:0035690 |
cellular response to drug |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease. |
IEA |
BP |
GO:0042594 |
response to starvation |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment. |
IEA |
BP |
GO:0044208 |
de novo' AMP biosynthetic process |
The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP). |
IBA|IEA |
BP |
GO:0046040 |
IMP metabolic process |
The chemical reactions and pathways involving IMP, inosine monophosphate. |
IBA |
BP |
GO:0071257 |
cellular response to electrical stimulus |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. |
IEA |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
MF |
GO:0000287 |
magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. |
IEA |
MF |
GO:0003924 |
GTPase activity |
Catalysis of the reaction: GTP + H2O = GDP + phosphate. |
IEA |
MF |
GO:0004019 |
adenylosuccinate synthase activity |
Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate. |
EXP|IDA |
MF |
GO:0005525 |
GTP binding |
Interacting selectively and non-covalently with GTP, guanosine triphosphate. |
NAS |
MF |
GO:0042301 |
phosphate ion binding |
Interacting selectively and non-covalently with phosphate. |
NAS |
MF |
GO:0042803 |
protein homodimerization activity |
Interacting selectively and non-covalently with an identical protein to form a homodimer. |
IEA |
MF |
GO:0051015 |
actin filament binding |
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits. |
IEA |
Domain ID | Description |
---|---|
IPR001114 |
Adenylosuccinate synthetase |
IPR018220 |
Adenylosuccinate synthase, GTP-binding site |
IPR027417 |
P-loop containing nucleoside triphosphate hydrolase |
IPR027509 |
Adenylosuccinate synthetase isozyme 1, chordates |
IPR033128 |
Adenylosuccinate synthase, active site |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00230 |
Purine metabolism |
KEGG |
hsa00250 |
Alanine, aspartate and glutamate metabolism |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
ADSSL1 |
122622 |
Q8N142 |
0.61 |
LYAR |
55646 |
Q9NX58 |
0.63 |
AZIN1 |
51582 |
O14977 |
0.63 |
YWHAZ |
7534 |
P63104 |
0.68 |