Protein Description

Gene Symbol ADSSL1
Entrez ID 122622
Uniprot ID Q8N142
Description adenylosuccinate synthase like 1
Chromosomal Location chr14: 104,724,186-104,747,325
Ontology GO ID GO Term Definition Evidence

BP

GO:0002376

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

NAS

BP

GO:0006167

AMP biosynthetic process

The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.

IDA

BP

GO:0006531

aspartate metabolic process

The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.

IEA

BP

GO:0006541

glutamine metabolic process

The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.

IEA

BP

GO:0009168

purine ribonucleoside monophosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.

TAS

BP

GO:0014850

response to muscle activity

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.

IEA

BP

GO:0035690

cellular response to drug

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.

IEA

BP

GO:0042594

response to starvation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.

IEA

BP

GO:0044208

de novo' AMP biosynthetic process

The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).

IBA|IEA

BP

GO:0046040

IMP metabolic process

The chemical reactions and pathways involving IMP, inosine monophosphate.

IBA

BP

GO:0071257

cellular response to electrical stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.

IEA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

IEA

MF

GO:0003924

GTPase activity

Catalysis of the reaction: GTP + H2O = GDP + phosphate.

IEA

MF

GO:0004019

adenylosuccinate synthase activity

Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.

EXP|IDA

MF

GO:0005525

GTP binding

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

NAS

MF

GO:0042301

phosphate ion binding

Interacting selectively and non-covalently with phosphate.

NAS

MF

GO:0042803

protein homodimerization activity

Interacting selectively and non-covalently with an identical protein to form a homodimer.

IEA

MF

GO:0051015

actin filament binding

Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.

IEA

Domain ID Description

IPR001114

Adenylosuccinate synthetase

IPR018220

Adenylosuccinate synthase, GTP-binding site

IPR027417

P-loop containing nucleoside triphosphate hydrolase

IPR027509

Adenylosuccinate synthetase isozyme 1, chordates

IPR033128

Adenylosuccinate synthase, active site

Pathway ID Pathway Term Pathway Source

hsa00230

Purine metabolism

KEGG

hsa00250

Alanine, aspartate and glutamate metabolism

KEGG

hsa01100

Metabolic pathways

KEGG

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

ADSSL1

122622

Q8N142

0.61

LYAR

55646

Q9NX58

0.63

AZIN1

51582

O14977

0.63

YWHAZ

7534

P63104

0.68