Gene Symbol | TDRD9 |
Entrez ID | 122402 |
Uniprot ID | Q8NDG6 |
Description | tudor domain containing 9 |
Chromosomal Location | chr14: 103,928,462-104,052,667 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006396 |
RNA processing |
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. |
IBA |
BP |
GO:0007140 |
male meiosis |
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline. |
ISS |
BP |
GO:0007275 |
multicellular organism development |
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). |
IEA |
BP |
GO:0007283 |
spermatogenesis |
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis. |
ISS |
BP |
GO:0009566 |
fertilization |
The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). |
ISS |
BP |
GO:0030154 |
cell differentiation |
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
IEA |
BP |
GO:0031047 |
gene silencing by RNA |
Any process in which RNA molecules inactivate expression of target genes. |
IEA |
BP |
GO:0034587 |
piRNA metabolic process |
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. |
ISS |
BP |
GO:0043046 |
DNA methylation involved in gamete generation |
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete. |
ISS |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IBA|ISS |
CC |
GO:0043186 |
P granule |
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes. |
IBA |
CC |
GO:0071547 |
piP-body |
A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway. |
ISS |
MF |
GO:0004004 |
ATP-dependent RNA helicase activity |
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix. |
IBA |
MF |
GO:0005524 |
ATP binding |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
IEA |
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IBA |
Domain ID | Description |
---|---|
IPR001650 |
Helicase, C-terminal |
IPR002999 |
Tudor domain |
IPR007502 |
Helicase-associated domain |
IPR011545 |
DEAD/DEAH box helicase domain |
IPR014001 |
Helicase superfamily 1/2, ATP-binding domain |
IPR027417 |
P-loop containing nucleoside triphosphate hydrolase |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
PPP2R1A |
5518 |
P30153 |
0.63 |
DNAJC7 |
7266 |
Q99615 |
0.72 |