Protein Description

Gene Symbol TDRD9
Entrez ID 122402
Uniprot ID Q8NDG6
Description tudor domain containing 9
Chromosomal Location chr14: 103,928,462-104,052,667
Ontology GO ID GO Term Definition Evidence

BP

GO:0006396

RNA processing

Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

IBA

BP

GO:0007140

male meiosis

A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.

ISS

BP

GO:0007275

multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

IEA

BP

GO:0007283

spermatogenesis

The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.

ISS

BP

GO:0009566

fertilization

The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).

ISS

BP

GO:0030154

cell differentiation

The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

IEA

BP

GO:0031047

gene silencing by RNA

Any process in which RNA molecules inactivate expression of target genes.

IEA

BP

GO:0034587

piRNA metabolic process

The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.

ISS

BP

GO:0043046

DNA methylation involved in gamete generation

The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.

ISS

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IBA|ISS

CC

GO:0043186

P granule

A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.

IBA

CC

GO:0071547

piP-body

A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.

ISS

MF

GO:0004004

ATP-dependent RNA helicase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.

IBA

MF

GO:0005524

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

IEA

MF

GO:0044822

poly(A) RNA binding

Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.

IBA

Domain ID Description

IPR001650

Helicase, C-terminal

IPR002999

Tudor domain

IPR007502

Helicase-associated domain

IPR011545

DEAD/DEAH box helicase domain

IPR014001

Helicase superfamily 1/2, ATP-binding domain

IPR027417

P-loop containing nucleoside triphosphate hydrolase

No pathways found.

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

PPP2R1A

5518

P30153

0.63

DNAJC7

7266

Q99615

0.72