BP

GO:0006631

fatty acid metabolic process

The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.

IDA

BP

GO:0035338

long-chain fatty-acyl-CoA biosynthetic process

The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.

TAS

BP

GO:0043491

protein kinase B signaling

A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.

IMP

BP

GO:1902108

regulation of mitochondrial membrane permeability involved in apoptotic process

Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.

IMP

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IDA

CC

GO:0005743

mitochondrial inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

IEA

CC

GO:0005758

mitochondrial intermembrane space

The region between the inner and outer lipid bilayers of the mitochondrial envelope.

IEA

CC

GO:0005759

mitochondrial matrix

The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

TAS

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IDA|TAS

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

TAS

CC

GO:0032587

ruffle membrane

The portion of the plasma membrane surrounding a ruffle.

IEA

MF

GO:0016290

palmitoyl-CoA hydrolase activity

Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.

IDA

MF

GO:0047617

acyl-CoA hydrolase activity

Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate.

TAS