Gene Symbol | MRPL54 |
Entrez ID | 116541 |
Uniprot ID | Q6P161 |
Description | mitochondrial ribosomal protein L54 |
Chromosomal Location | chr19: 3,762,664-3,768,575 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0070125 |
mitochondrial translational elongation |
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. |
TAS |
BP |
GO:0070126 |
mitochondrial translational termination |
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa). |
TAS |
CC |
GO:0005743 |
mitochondrial inner membrane |
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
TAS |
CC |
GO:0005840 |
ribosome |
An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. |
IEA |
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
Domain ID | Description |
---|---|
IPR013870 |
Ribosomal protein L37, mitochondrial |
Tissue | Cell Type |
---|---|
appendix |
glandular cells |
appendix |
lymphoid tissue |
duodenum |
glandular cells |
esophagus |
squamous epithelial cells |
lung |
macrophages |
parathyroid gland |
glandular cells |
rectum |
glandular cells |
salivary gland |
glandular cells |
skin |
fibroblasts |
small intestine |
glandular cells |
spleen |
cells in white pulp |
stomach |
glandular cells |
tonsil |
germinal center cells |
tonsil |
non-germinal center cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
MRPS7 |
51081 |
Q9Y2R9 |
0.49 |
POLR3A |
11128 |
O14802 |
0.49 |
FAM50B |
26240 |
Q9Y247 |
0.49 |
NPM1 |
4869 |
P06748 |
0.63 |
KIAA0101 |
9768 |
Q15004 |
0.63 |
CENPA |
1058 |
P49450 |
0.72 |
ICT1 |
3396 |
Q14197 |
0.72 |
MRPL50 |
54534 |
Q8N5N7 |
0.72 |
VPS16 |
64601 |
Q9H269 |
0.72 |
MRPL9 |
65005 |
Q9BYD2 |
0.72 |