Protein Description

Gene Symbol MRPL54
Entrez ID 116541
Uniprot ID Q6P161
Description mitochondrial ribosomal protein L54
Chromosomal Location chr19: 3,762,664-3,768,575
Ontology GO ID GO Term Definition Evidence

BP

GO:0070125

mitochondrial translational elongation

The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.

TAS

BP

GO:0070126

mitochondrial translational termination

The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).

TAS

CC

GO:0005743

mitochondrial inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

TAS

CC

GO:0005840

ribosome

An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.

IEA

MF

GO:0044822

poly(A) RNA binding

Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.

IDA

Domain ID Description

IPR013870

Ribosomal protein L37, mitochondrial

No pathways found.

No diseases found.

Tissue Cell Type

appendix

glandular cells

appendix

lymphoid tissue

duodenum

glandular cells

esophagus

squamous epithelial cells

lung

macrophages

parathyroid gland

glandular cells

rectum

glandular cells

salivary gland

glandular cells

skin

fibroblasts

small intestine

glandular cells

spleen

cells in white pulp

stomach

glandular cells

tonsil

germinal center cells

tonsil

non-germinal center cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

MRPS7

51081

Q9Y2R9

0.49

POLR3A

11128

O14802

0.49

FAM50B

26240

Q9Y247

0.49

NPM1

4869

P06748

0.63

KIAA0101

9768

Q15004

0.63

CENPA

1058

P49450

0.72

ICT1

3396

Q14197

0.72

MRPL50

54534

Q8N5N7

0.72

VPS16

64601

Q9H269

0.72

MRPL9

65005

Q9BYD2

0.72