| Gene Symbol | FBXO44 |
| Entrez ID | 93611 |
| Uniprot ID | Q9H4M3 |
| Description | F-box protein 44 |
| Chromosomal Location | chr1: 11,654,375-11,663,327 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
CC |
GO:0019005 |
SCF ubiquitin ligase complex |
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
| Domain ID | Description |
|---|---|
|
IPR001810 |
F-box domain |
|
IPR007397 |
F-box associated (FBA) domain |
|
IPR008979 |
Galactose-binding domain-like |
| UMLS CUI | UMLS Term |
|---|---|
|
C0033578 |
Prostatic Neoplasms |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
lung |
pneumocytes |
|
nasopharynx |
respiratory epithelial cells |
|
ovary |
ovarian stroma cells |
|
pancreas |
exocrine glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
skin |
melanocytes |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
| Database Name |
|---|
|
DisGeNET |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
21411543 |
Savaris et al. |
2011 |
Progesterone Resistance in PCOS Endometrium: A Microarray Analysis in Clomiphene Citrate-Treated and Artificial Menstrual Cycles |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
BARD1 |
580 |
Q99728 |
0.63 |
|
CUL4B |
8450 |
Q13620 |
0.63 |
|
SPA17 |
53340 |
Q15506 |
0.63 |
|
DDB1 |
100290337 |
Q16531 |
0.63 |
|
RBX1 |
9978 |
P62877 |
0.73 |
|
CUL1 |
8454 |
Q13616 |
0.74 |
|
SKP1 |
6500 |
P63208 |
0.90 |
|
RGS2 |
5997 |
P41220 |
0.63 |
|
CDK13 |
8621 |
Q14004 |
0.63 |
|
COPS5 |
10987 |
Q92905 |
0.63 |
|
ECM29 |
23392 |
Q5VYK3 |
0.63 |
|
SERTAD3 |
29946 |
Q9UJW9 |
0.63 |
|
BRCA1 |
672 |
P38398 |
0.65 |
|
C17orf59 |
54785 |
Q96GS4 |
0.73 |
|
COPS6 |
10980 |
Q7L5N1 |
0.86 |