| Gene Symbol | ARRDC4 |
| Entrez ID | 91947 |
| Uniprot ID | Q8NCT1 |
| Description | arrestin domain containing 4 |
| Chromosomal Location | chr15: 97,960,698-97,973,838 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0051443 | positive regulation of ubiquitin-protein transferase activity |
Any process that activates, maintains or increases the rate of ubiquitin transferase activity. | IPI |
CC | GO:0005768 | endosome |
A vacuole to which materials ingested by endocytosis are delivered. | IDA |
CC | GO:0005769 | early endosome |
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. | IEA |
CC | GO:0005886 | plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. | IDA |
CC | GO:0016023 | cytoplasmic, membrane-bounded vesicle |
A membrane-bounded vesicle found in the cytoplasm of the cell. | IEA |
| Domain ID | Description |
|---|---|
IPR011021 | Arrestin-like, N-terminal |
IPR011022 | Arrestin C-terminal-like domain |
IPR014756 | Immunoglobulin E-set |
| Tissue | Cell Type |
|---|---|
adrenal gland | glandular cells |
bone marrow | hematopoietic cells |
bronchus | respiratory epithelial cells |
cerebellum | Purkinje cells |
colon | glandular cells |
colon | peripheral nerve/ganglion |
duodenum | glandular cells |
gallbladder | glandular cells |
heart muscle | myocytes |
nasopharynx | respiratory epithelial cells |
pancreas | exocrine glandular cells |
placenta | trophoblastic cells |
rectum | glandular cells |
skeletal muscle | myocytes |
skin | fibroblasts |
small intestine | glandular cells |
smooth muscle | smooth muscle cells |
stomach | glandular cells |
thyroid gland | glandular cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22617121 | Ouandaogo et al. | 2012 | Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
NEDD4 | 4734 | P46934 | 0.52 |
ADRB2 | 154 | P07550 | 0.63 |
ARRB1 | 408 | P49407 | 0.63 |
AVPR2 | 554 | P30518 | 0.63 |
CLTC | 1213 | Q00610 | 0.63 |
HGS | 9146 | O14964 | 0.63 |
WWP2 | 11060 | O00308 | 0.63 |
NEDD4L | 23327 | Q96PU5 | 0.63 |
ITCH | 83737 | Q96J02 | 0.63 |
ARRB2 | 409 | P32121 | 0.65 |