Protein Description

Gene Symbol EPYC
Entrez ID 1833
Uniprot ID Q99645
Description epiphycan
Chromosomal Location chr12: 90,963,679-91,005,026
Ontology GO ID GO Term Definition Evidence

BP

GO:0007409

axonogenesis

De novo generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells. Refers to the morphogenesis or creation of shape or form of the developing axon.

IBA

BP

GO:0007565

female pregnancy

The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.

TAS

CC

GO:0005578

proteinaceous extracellular matrix

A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.

IBA

CC

GO:0005615

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

IBA

MF

GO:0005539

glycosaminoglycan binding

Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.

TAS

MF

GO:0008201

heparin binding

Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.

IBA

Domain ID Description

IPR000372

Leucine-rich repeat N-terminal domain

IPR001611

Leucine-rich repeat

IPR003591

Leucine-rich repeat, typical subtype

IPR027217

Epiphycan

IPR032675

Leucine-rich repeat domain, L domain-like

Pathway ID Pathway Term Pathway Source

h_slrpPathway

Small Leucine-rich Proteoglycan (SLRP) molecules,

BioCarta

No diseases found.

Tissue Cell Type

colon

endothelial cells

skin

fibroblasts

soft tissue

fibroblasts

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

PLCG2

5336

P16885

0.63

CRK

1398

P46108

0.63