Protein Description

Gene Symbol GADD45GIP1
Entrez ID 90480
Uniprot ID Q8TAE8
Description GADD45G interacting protein 1
Chromosomal Location chr19: 12,953,119-12,957,236
Ontology GO ID GO Term Definition Evidence

BP

GO:0008284

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

IEA

BP

GO:0016032

viral process

A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.

IEA

BP

GO:0070125

mitochondrial translational elongation

The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.

TAS

BP

GO:0070126

mitochondrial translational termination

The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).

TAS

BP

GO:0071850

mitotic cell cycle arrest

The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M).

IDA

BP

GO:1903862

positive regulation of oxidative phosphorylation

Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation.

IEA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IEA

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IDA

CC

GO:0005759

mitochondrial matrix

The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

TAS

CC

GO:0005761

mitochondrial ribosome

A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

Domain ID Description

IPR018472

Growth arrest/ DNA-damage-inducible protein-interacting protein 1

No pathways found.

No diseases found.

Tissue Cell Type

appendix

glandular cells

bronchus

respiratory epithelial cells

colon

glandular cells

duodenum

glandular cells

endometrium

glandular cells

esophagus

squamous epithelial cells

gallbladder

glandular cells

kidney

cells in tubules

nasopharynx

respiratory epithelial cells

parathyroid gland

glandular cells

rectum

glandular cells

salivary gland

glandular cells

small intestine

glandular cells

thyroid gland

glandular cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

25393639

Ambekar et al.

2014

Proteomics of follicular fluid from women with polycystic ovary syndrome suggests molecular defects in follicular development

Gene Symbol Entrez ID Uniprot ID Score

MRPL12

6182

P52815

0.49

TAP1

6890

Q03518

0.49

PTRH2

51651

Q9Y3E5

0.49

TSR1

55720

Q2NL82

0.49

MRPL14

64928

Q6P1L8

0.49

MRPL11

65003

Q9Y3B7

0.49

TMEM177

80775

Q53S58

0.49

APP

351

P05067

0.56

NFE2L2

4780

Q16236

0.63

RPL31

6160

P62899

0.63

ELF3

1999

P78545

0.65

CSNK2B

1460

P67870

0.75

NR4A1

3164

P22736

0.77

GADD45A

1647

P24522

0.79

GADD45B

4616

O75293

0.79

GADD45G

10912

O95257

0.79

EIF3C

8663

Q99613

0.49

ABCE1

6059

P61221

0.63

RPL13

6137

P26373

0.63

RPS8

6202

P62241

0.63

HIST1H3A

8350

P68431

0.63

MRPL28

10573

Q13084

0.63

MRPS30

10884

Q9NP92

0.63

COPS5

10987

Q92905

0.63

UPF2

26019

Q9HAU5

0.63

MRPL4

51073

Q9BYD3

0.63

MRPL37

51253

Q9BZE1

0.63

EXOSC4

54512

Q9NPD3

0.63

MRPL47

57129

Q9HD33

0.63

LIN28A

79727

Q9H9Z2

0.63

CCDC8

83987

Q9H0W5

0.63

NIFK

84365

Q9BYG3

0.63

IKBKG

8517

Q9Y6K9

0.68

FOXL2

668

P58012

0.72

FOXL1

2300

Q12952

0.72

FOXS1

2307

O43638

0.72

ICT1

3396

Q14197

0.72

KIF2A

3796

O00139

0.72

RAB5C

5878

P51148

0.72

FOXB1

27023

Q99853

0.72

MRPL50

54534

Q8N5N7

0.72

KRBOX4

55634

Q5JUW0

0.72

MRPL9

65005

Q9BYD2

0.72

MRPL1

65008

Q9BYD6

0.72

HNRNPA1

3178

P09651

0.73

FBXW11

23291

Q9UKB1

0.73

AR

367

P10275

0.75

STAT3

6774

P40763

0.93