Gene Symbol | KLHL13 |
Entrez ID | 90293 |
Uniprot ID | Q9P2N7 |
Description | kelch like family member 13 |
Chromosomal Location | chrX: 117,897,813-118,117,340 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0000910 |
cytokinesis |
The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells. |
IMP |
BP |
GO:0007067 |
mitotic nuclear division |
A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. |
IEA |
BP |
GO:0016567 |
protein ubiquitination |
The process in which one or more ubiquitin groups are added to a protein. |
IDA|IEA |
CC |
GO:0030496 |
midbody |
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis. |
IBA |
CC |
GO:0031463 |
Cul3-RING ubiquitin ligase complex |
A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein. |
IDA |
MF |
GO:0004842 |
ubiquitin-protein transferase activity |
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. |
IDA |
Domain ID | Description |
---|---|
IPR000210 |
BTB/POZ domain |
IPR006652 |
Kelch repeat type 1 |
IPR011333 |
SKP1/BTB/POZ domain |
IPR011705 |
BTB/Kelch-associated |
IPR015915 |
Kelch-type beta propeller |
IPR017096 |
BTB-kelch protein |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa04120 |
Ubiquitin mediated proteolysis |
KEGG |
Tissue | Cell Type |
---|---|
smooth muscle |
smooth muscle cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
HSP90AB1 |
3326 |
P08238 |
0.49 |
UBE2D1 |
7321 |
P51668 |
0.56 |
USP25 |
29761 |
Q9UHP3 |
0.72 |
MAD2L1 |
4085 |
Q13257 |
0.76 |
USP11 |
8237 |
P51784 |
0.76 |
ZMYM4 |
9202 |
Q5VZL5 |
0.76 |
ZMYM6 |
9204 |
O95789 |
0.76 |
COPS2 |
9318 |
P61201 |
0.76 |
NUDCD3 |
23386 |
Q8IVD9 |
0.76 |
COPS4 |
51138 |
Q9BT78 |
0.76 |
AURKB |
9212 |
Q96GD4 |
0.80 |
KLHL22 |
84861 |
Q53GT1 |
0.86 |
KLHL9 |
55958 |
Q9P2J3 |
0.87 |
HSP90AA1 |
3320 |
P07900 |
0.63 |
NEDD8 |
4738 |
Q15843 |
0.63 |
NTRK1 |
4914 |
P04629 |
0.63 |
KLHL21 |
9903 |
Q9UJP4 |
0.63 |
DCUN1D1 |
54165 |
Q96GG9 |
0.63 |
CSPP1 |
79848 |
Q1MSJ5 |
0.63 |
KIFC3 |
3801 |
Q9BVG8 |
0.72 |
PRPS1 |
5631 |
P60891 |
0.72 |
TFG |
10342 |
Q92734 |
0.72 |
TRIM29 |
23650 |
Q14134 |
0.72 |
UBXN7 |
26043 |
O94888 |
0.72 |
COPS7A |
50813 |
Q9UBW8 |
0.72 |
CUL3 |
8452 |
Q13618 |
0.74 |
COPS6 |
10980 |
Q7L5N1 |
0.86 |
COPS5 |
10987 |
Q92905 |
0.86 |