Protein Description

Gene Symbol NAV2
Entrez ID 89797
Uniprot ID Q8IVL1
Description neuron navigator 2
Chromosomal Location chr11: 19,350,724-20,121,598
Ontology GO ID GO Term Definition Evidence

BP

GO:0003025

regulation of systemic arterial blood pressure by baroreceptor feedback

The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control.

IEA

BP

GO:0007605

sensory perception of sound

The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.

IEA

BP

GO:0007608

sensory perception of smell

The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.

IEA

BP

GO:0007626

locomotory behavior

The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

IEA

BP

GO:0021554

optic nerve development

The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.

IEA

BP

GO:0021563

glossopharyngeal nerve development

Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.

IEA

BP

GO:0021564

vagus nerve development

The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.

IEA

CC

GO:0005614

interstitial matrix

A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.

IEA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

MF

GO:0004386

helicase activity

Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix.

IEA

MF

GO:0005524

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

IEA

MF

GO:0008201

heparin binding

Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.

IEA

Domain ID Description

IPR001715

Calponin homology domain

IPR003593

AAA+ ATPase domain

IPR027417

P-loop containing nucleoside triphosphate hydrolase

No pathways found.

UMLS CUI UMLS Term

C0019158

Hepatitis

Tissue Cell Type

appendix

glandular cells

breast

glandular cells

colon

glandular cells

duodenum

glandular cells

esophagus

squamous epithelial cells

gallbladder

glandular cells

kidney

cells in tubules

parathyroid gland

glandular cells

placenta

decidual cells

placenta

trophoblastic cells

rectum

glandular cells

seminal vesicle

glandular cells

small intestine

glandular cells

stomach

glandular cells

thyroid gland

glandular cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

RRAS

6237

P10301

0.52

ADAT2

134637

Q7Z6V5

0.63

CFAP58

159686

Q5T655

0.63

ING5

84289

Q8WYH8

0.73

APC

324

P25054

0.63

MYC

4609

P01106

0.63

TRIO

7204

O75962

0.63

HDAC6

10013

Q9UBN7

0.63

MORF4L1

10933

Q9UBU8

0.63

MAPRE1

22919

Q15691

0.63

RBM15B

29890

Q8NDT2

0.63

ING4

51147

Q9UNL4

0.63

RBM15

64783

Q96T37

0.63

PIAS2

9063

O75928

0.73