Protein Description

Gene Symbol ZNF518B
Entrez ID 85460
Uniprot ID Q9C0D4
Description zinc finger protein 518B
Chromosomal Location chr4: 10,439,874-10,457,410
Ontology GO ID GO Term Definition Evidence

BP

GO:0006351

transcription, DNA-templated

The cellular synthesis of RNA on a template of DNA.

IEA

BP

GO:0006357

regulation of transcription from RNA polymerase II promoter

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.

IEA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IBA

MF

GO:0000981

RNA polymerase II transcription factor activity, sequence-specific DNA binding

Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.

IBA

MF

GO:0003677

DNA binding

Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

IEA

MF

GO:0046872

metal ion binding

Interacting selectively and non-covalently with any metal ion.

IEA

Domain ID Description

IPR013087

Zinc finger C2H2-type

IPR027775

C2H2- zinc finger protein family subset

IPR028379

Zinc finger protein 518B

No pathways found.

No diseases found.

Tissue Cell Type

adrenal gland

glandular cells

bone marrow

hematopoietic cells

breast

glandular cells

bronchus

respiratory epithelial cells

cerebellum

cells in molecular layer

cerebral cortex

neuronal cells

cervix, uterine

glandular cells

cervix, uterine

squamous epithelial cells

colon

glandular cells

duodenum

glandular cells

epididymis

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

hippocampus

glial cells

kidney

cells in tubules

nasopharynx

respiratory epithelial cells

placenta

decidual cells

placenta

trophoblastic cells

rectum

glandular cells

skin

keratinocytes

skin

Langerhans

skin

melanocytes

skin

epidermal cells

stomach

glandular cells

testis

cells in seminiferous ducts

testis

Leydig cells

thyroid gland

glandular cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

SEC23IP

11196

Q9Y6Y8

0.49