| Gene Symbol | HIST1H2BK |
| Entrez ID | 85236 |
| Uniprot ID | O60814 |
| Description | histone cluster 1, H2bk |
| Chromosomal Location | chr6: 27,146,418-27,146,798 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0002227 |
innate immune response in mucosa |
Any process of the innate immune response that takes place in the mucosal tissues. |
IDA |
|
BP |
GO:0006334 |
nucleosome assembly |
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. |
IBA |
|
BP |
GO:0019731 |
antibacterial humoral response |
An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster. |
IDA |
|
BP |
GO:0050830 |
defense response to Gram-positive bacterium |
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism. |
IDA |
|
CC |
GO:0000788 |
nuclear nucleosome |
A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the nucleus into higher order structures. |
IBA |
|
CC |
GO:0005615 |
extracellular space |
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
IDA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA|TAS |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
|
MF |
GO:0003674 |
molecular_function |
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
ND |
|
MF |
GO:0003677 |
DNA binding |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
IBA |
|
MF |
GO:0046982 |
protein heterodimerization activity |
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR000558 |
Histone H2B |
|
IPR007125 |
Histone H2A/H2B/H3 |
|
IPR009072 |
Histone-fold |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa05034 |
Alcoholism |
KEGG |
|
hsa05203 |
Viral carcinogenesis |
KEGG |
|
hsa05322 |
Systemic lupus erythematosus |
KEGG |
| UMLS CUI | UMLS Term |
|---|---|
|
C1458155 |
Mammary Neoplasms |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
bone marrow |
hematopoietic cells |
|
breast |
adipocytes |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
cells in molecular layer |
|
cerebral cortex |
glial cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
hippocampus |
glial cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
liver |
bile duct cells |
|
liver |
hepatocytes |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
follicle cells |
|
ovary |
ovarian stroma cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
soft tissue |
adipocytes |
|
soft tissue |
fibroblasts |
|
soft tissue |
peripheral nerve |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
12734205 |
Wood et al. |
2003 |
The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis |
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
HIRIP3 |
8479 |
Q9BW71 |
0.49 |
|
CLK1 |
1195 |
P49759 |
0.52 |
|
SRPK2 |
6733 |
P78362 |
0.52 |
|
RNF40 |
9810 |
O75150 |
0.52 |
|
RNF20 |
56254 |
Q5VTR2 |
0.52 |
|
CD81 |
975 |
P60033 |
0.63 |
|
FN1 |
2335 |
P02751 |
0.63 |
|
ICAM1 |
3383 |
P05362 |
0.63 |
|
KIF11 |
3832 |
P52732 |
0.63 |
|
MCM2 |
4171 |
P49736 |
0.63 |
|
MCM5 |
4174 |
P33992 |
0.63 |
|
PRKCD |
5580 |
Q05655 |
0.63 |
|
SUMO2 |
6613 |
P61956 |
0.63 |
|
VCAM1 |
7412 |
P19320 |
0.63 |
|
CHD1L |
9557 |
Q86WJ1 |
0.63 |
|
HDAC5 |
10014 |
Q9UQL6 |
0.63 |
|
CBX8 |
57332 |
Q9HC52 |
0.63 |
|
SPRTN |
83932 |
Q9H040 |
0.63 |
|
IGSF8 |
93185 |
Q969P0 |
0.63 |
|
CEP170P1 |
645455 |
Q96L14 |
0.63 |
|
HDGF |
3068 |
P51858 |
0.72 |
|
HIRA |
7290 |
P54198 |
0.77 |