| Gene Symbol | RAB2B |
| Entrez ID | 84932 |
| Uniprot ID | Q8WUD1 |
| Description | RAB2B, member RAS oncogene family |
| Chromosomal Location | chr14: 21,459,020-21,476,973 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0007264 | small GTPase mediated signal transduction |
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals. | IEA |
BP | GO:0015031 | protein transport |
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. | IEA |
BP | GO:0016192 | vesicle-mediated transport |
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. | IEA |
BP | GO:0045921 | positive regulation of exocytosis |
Any process that activates or increases the frequency, rate or extent of exocytosis. | IMP |
CC | GO:0000139 | Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. | IEA |
CC | GO:0005789 | endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. | IEA |
CC | GO:0005886 | plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. | IEA |
CC | GO:0070062 | extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. | IDA |
MF | GO:0005515 | protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). | IPI |
MF | GO:0005525 | GTP binding |
Interacting selectively and non-covalently with GTP, guanosine triphosphate. | IEA |
| Domain ID | Description |
|---|---|
IPR001806 | Small GTPase superfamily |
IPR005225 | Small GTP-binding protein domain |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
SMAD1 | 4086 | Q15797 | 0.52 |
SMAD4 | 4089 | Q13485 | 0.52 |
APP | 351 | P05067 | 0.56 |
CRK | 1398 | P46108 | 0.63 |
FAM114A1 | 92689 | Q8IWE2 | 0.63 |
FAM71C | 196472 | Q8NEG0 | 0.63 |
ELAVL1 | 1994 | Q15717 | 0.63 |
GOLGA2 | 2801 | Q08379 | 0.63 |
ICA1 | 3382 | Q05084 | 0.63 |
BLZF1 | 8548 | Q9H2G9 | 0.63 |
BAG3 | 9531 | O95817 | 0.63 |
ADAMTSL4 | 54507 | Q6UY14 | 0.63 |
ATF2 | 1386 | P15336 | 0.72 |