Gene Symbol | RAB2B |
Entrez ID | 84932 |
Uniprot ID | Q8WUD1 |
Description | RAB2B, member RAS oncogene family |
Chromosomal Location | chr14: 21,459,020-21,476,973 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007264 |
small GTPase mediated signal transduction |
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals. |
IEA |
BP |
GO:0015031 |
protein transport |
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IEA |
BP |
GO:0016192 |
vesicle-mediated transport |
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. |
IEA |
BP |
GO:0045921 |
positive regulation of exocytosis |
Any process that activates or increases the frequency, rate or extent of exocytosis. |
IMP |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
IEA |
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
IEA |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IEA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0005525 |
GTP binding |
Interacting selectively and non-covalently with GTP, guanosine triphosphate. |
IEA |
Domain ID | Description |
---|---|
IPR001806 |
Small GTPase superfamily |
IPR005225 |
Small GTP-binding protein domain |
IPR027417 |
P-loop containing nucleoside triphosphate hydrolase |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
SMAD1 |
4086 |
Q15797 |
0.52 |
SMAD4 |
4089 |
Q13485 |
0.52 |
APP |
351 |
P05067 |
0.56 |
CRK |
1398 |
P46108 |
0.63 |
FAM114A1 |
92689 |
Q8IWE2 |
0.63 |
FAM71C |
196472 |
Q8NEG0 |
0.63 |
ELAVL1 |
1994 |
Q15717 |
0.63 |
GOLGA2 |
2801 |
Q08379 |
0.63 |
ICA1 |
3382 |
Q05084 |
0.63 |
BLZF1 |
8548 |
Q9H2G9 |
0.63 |
BAG3 |
9531 |
O95817 |
0.63 |
ADAMTSL4 |
54507 |
Q6UY14 |
0.63 |
ATF2 |
1386 |
P15336 |
0.72 |