Protein Description

Gene Symbol RAB2B
Entrez ID 84932
Uniprot ID Q8WUD1
Description RAB2B, member RAS oncogene family
Chromosomal Location chr14: 21,459,020-21,476,973
Ontology GO ID GO Term Definition Evidence

BP

GO:0007264

small GTPase mediated signal transduction

Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.

IEA

BP

GO:0015031

protein transport

The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

IEA

BP

GO:0016192

vesicle-mediated transport

A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.

IEA

BP

GO:0045921

positive regulation of exocytosis

Any process that activates or increases the frequency, rate or extent of exocytosis.

IMP

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IEA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IEA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IEA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0005525

GTP binding

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

IEA

Domain ID Description

IPR001806

Small GTPase superfamily

IPR005225

Small GTP-binding protein domain

IPR027417

P-loop containing nucleoside triphosphate hydrolase

No pathways found.

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

SMAD1

4086

Q15797

0.52

SMAD4

4089

Q13485

0.52

APP

351

P05067

0.56

CRK

1398

P46108

0.63

FAM114A1

92689

Q8IWE2

0.63

FAM71C

196472

Q8NEG0

0.63

ELAVL1

1994

Q15717

0.63

GOLGA2

2801

Q08379

0.63

ICA1

3382

Q05084

0.63

BLZF1

8548

Q9H2G9

0.63

BAG3

9531

O95817

0.63

ADAMTSL4

54507

Q6UY14

0.63

ATF2

1386

P15336

0.72