Gene Symbol | GPAT3 |
Entrez ID | 84803 |
Uniprot ID | Q53EU6 |
Description | glycerol-3-phosphate acyltransferase 3 |
Chromosomal Location | chr4: 83,535,914-83,605,875 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006654 |
phosphatidic acid biosynthetic process |
The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids. |
TAS |
BP |
GO:0016024 |
CDP-diacylglycerol biosynthetic process |
The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. |
IEA |
BP |
GO:0019432 |
triglyceride biosynthetic process |
The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol. |
IDA|IEA|TAS |
BP |
GO:0032006 |
regulation of TOR signaling |
Any process that modulates the frequency, rate or extent of TOR signaling. |
IDA |
CC |
GO:0005783 |
endoplasmic reticulum |
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
IDA |
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
IDA|TAS |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
MF |
GO:0003841 |
1-acylglycerol-3-phosphate O-acyltransferase activity |
Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate. |
TAS |
MF |
GO:0004366 |
glycerol-3-phosphate O-acyltransferase activity |
Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate. |
IDA |
Domain ID | Description |
---|---|
IPR002123 |
Phospholipid/glycerol acyltransferase |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00561 |
Glycerolipid metabolism |
KEGG |
hsa00564 |
Glycerophospholipid metabolism |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
Tissue | Cell Type |
---|---|
appendix |
glandular cells |
breast |
glandular cells |
breast |
myoepithelial cells |
bronchus |
respiratory epithelial cells |
caudate |
neuronal cells |
cerebellum |
cells in molecular layer |
cerebellum |
Purkinje cells |
cerebral cortex |
neuronal cells |
cervix, uterine |
glandular cells |
colon |
glandular cells |
colon |
peripheral nerve/ganglion |
duodenum |
glandular cells |
endometrium |
glandular cells |
epididymis |
glandular cells |
esophagus |
squamous epithelial cells |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
hippocampus |
neuronal cells |
kidney |
cells in tubules |
nasopharynx |
respiratory epithelial cells |
ovary |
follicle cells |
pancreas |
exocrine glandular cells |
pancreas |
islets of Langerhans |
rectum |
glandular cells |
skin |
epidermal cells |
small intestine |
glandular cells |
stomach |
glandular cells |
testis |
cells in seminiferous ducts |
thyroid gland |
glandular cells |
tonsil |
squamous epithelial cells |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
TCTN3 |
26123 |
Q6NUS6 |
0.49 |
TMEM216 |
51259 |
Q9P0N5 |
0.49 |
TCTN2 |
79867 |
Q96GX1 |
0.49 |
TMEM17 |
200728 |
Q86X19 |
0.49 |
ELAVL1 |
1994 |
Q15717 |
0.63 |
HLA-DPA1 |
3113 |
P20036 |
0.63 |
TSPAN17 |
26262 |
Q96FV3 |
0.63 |
SLC39A4 |
55630 |
Q6P5W5 |
0.63 |