Protein Description

Gene Symbol GPAT3
Entrez ID 84803
Uniprot ID Q53EU6
Description glycerol-3-phosphate acyltransferase 3
Chromosomal Location chr4: 83,535,914-83,605,875
Ontology GO ID GO Term Definition Evidence

BP

GO:0006654

phosphatidic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.

TAS

BP

GO:0016024

CDP-diacylglycerol biosynthetic process

The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.

IEA

BP

GO:0019432

triglyceride biosynthetic process

The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.

IDA|IEA|TAS

BP

GO:0032006

regulation of TOR signaling

Any process that modulates the frequency, rate or extent of TOR signaling.

IDA

CC

GO:0005783

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

IDA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IDA|TAS

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

MF

GO:0003841

1-acylglycerol-3-phosphate O-acyltransferase activity

Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.

TAS

MF

GO:0004366

glycerol-3-phosphate O-acyltransferase activity

Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.

IDA

Domain ID Description

IPR002123

Phospholipid/glycerol acyltransferase

Pathway ID Pathway Term Pathway Source

hsa00561

Glycerolipid metabolism

KEGG

hsa00564

Glycerophospholipid metabolism

KEGG

hsa01100

Metabolic pathways

KEGG

No diseases found.

Tissue Cell Type

appendix

glandular cells

breast

glandular cells

breast

myoepithelial cells

bronchus

respiratory epithelial cells

caudate

neuronal cells

cerebellum

cells in molecular layer

cerebellum

Purkinje cells

cerebral cortex

neuronal cells

cervix, uterine

glandular cells

colon

glandular cells

colon

peripheral nerve/ganglion

duodenum

glandular cells

endometrium

glandular cells

epididymis

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

hippocampus

neuronal cells

kidney

cells in tubules

nasopharynx

respiratory epithelial cells

ovary

follicle cells

pancreas

exocrine glandular cells

pancreas

islets of Langerhans

rectum

glandular cells

skin

epidermal cells

small intestine

glandular cells

stomach

glandular cells

testis

cells in seminiferous ducts

thyroid gland

glandular cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

TCTN3

26123

Q6NUS6

0.49

TMEM216

51259

Q9P0N5

0.49

TCTN2

79867

Q96GX1

0.49

TMEM17

200728

Q86X19

0.49

ELAVL1

1994

Q15717

0.63

HLA-DPA1

3113

P20036

0.63

TSPAN17

26262

Q96FV3

0.63

SLC39A4

55630

Q6P5W5

0.63