| Gene Symbol | GLYR1 |
| Entrez ID | 84656 |
| Uniprot ID | Q49A26 |
| Description | glyoxylate reductase 1 homolog (Arabidopsis) |
| Chromosomal Location | chr16: 4,803,203-4,847,342 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0055114 |
oxidation-reduction process |
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
IEA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
|
CC |
GO:0005794 |
Golgi apparatus |
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions. |
IDA |
|
MF |
GO:0003677 |
DNA binding |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
IEA |
|
MF |
GO:0004616 |
phosphogluconate dehydrogenase (decarboxylating) activity |
Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+. |
IEA |
|
MF |
GO:0035064 |
methylated histone binding |
Interacting selectively and non-covalently with a histone protein in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. |
IDA |
|
MF |
GO:0051287 |
NAD binding |
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR000313 |
PWWP domain |
|
IPR006115 |
6-phosphogluconate dehydrogenase, NADP-binding |
|
IPR008927 |
6-phosphogluconate dehydrogenase C-terminal domain-like |
|
IPR013328 |
6-phosphogluconate dehydrogenase, domain 2 |
|
IPR016040 |
NAD(P)-binding domain |
|
IPR029154 |
3-hydroxyisobutyrate dehydrogenase, NAD-binding domain |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
bone marrow |
hematopoietic cells |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
endothelial cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
colon |
peripheral nerve/ganglion |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
hippocampus |
glial cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
liver |
bile duct cells |
|
liver |
hepatocytes |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
ovarian stroma cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
fibroblasts |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
soft tissue |
adipocytes |
|
soft tissue |
fibroblasts |
|
soft tissue |
peripheral nerve |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
NOC2L |
26155 |
Q9Y3T9 |
0.49 |
|
BLK |
640 |
P51451 |
0.63 |
|
FNTB |
2342 |
P49356 |
0.63 |
|
HAL |
3034 |
P42357 |
0.63 |
|
LCP1 |
3936 |
P13796 |
0.63 |
|
NEFH |
4744 |
P12036 |
0.63 |
|
ALOXE3 |
59344 |
Q9BYJ1 |
0.63 |
|
CAPNS2 |
84290 |
Q96L46 |
0.63 |
|
SERPINA12 |
145264 |
Q8IW75 |
0.63 |
|
C6orf165 |
154313 |
Q8IYR0 |
0.63 |
|
KDM1B |
221656 |
Q8NB78 |
0.63 |
|
KDM1A |
23028 |
O60341 |
0.72 |
|
WHSC1L1 |
54904 |
Q9BZ95 |
0.72 |
|
RCC1 |
1104 |
P18754 |
0.49 |
|
DHX9 |
1660 |
Q08211 |
0.49 |
|
FBL |
2091 |
P22087 |
0.49 |
|
RFC1 |
5981 |
P35251 |
0.49 |
|
TOP2A |
7153 |
P11388 |
0.49 |
|
TOP2B |
7155 |
Q02880 |
0.49 |
|
HIST3H3 |
8290 |
Q16695 |
0.49 |
|
DDX18 |
8886 |
Q9NVP1 |
0.49 |
|
NOP58 |
51602 |
Q9Y2X3 |
0.49 |
|
FOXL2 |
668 |
P58012 |
0.63 |
|
CCNC |
892 |
P24863 |
0.63 |
|
ELAVL1 |
1994 |
Q15717 |
0.63 |
|
ESR1 |
2099 |
P03372 |
0.63 |
|
FHL2 |
2274 |
Q14192 |
0.63 |
|
IFI16 |
3428 |
Q16666 |
0.63 |
|
ILF2 |
3608 |
Q12905 |
0.63 |
|
MAGEA1 |
4100 |
P43355 |
0.63 |
|
MNDA |
4332 |
P41218 |
0.63 |
|
NPM1 |
4869 |
P06748 |
0.63 |
|
YBX1 |
4904 |
P67809 |
0.63 |
|
RNF2 |
6045 |
Q99496 |
0.63 |
|
RPL8 |
6132 |
P62917 |
0.63 |
|
SUMO1 |
7341 |
P63165 |
0.63 |
|
HIST1H3A |
8350 |
P68431 |
0.63 |
|
EED |
8726 |
O75530 |
0.63 |
|
SUZ12 |
23512 |
Q15022 |
0.63 |
|
MED4 |
29079 |
Q9NPJ6 |
0.63 |
|
GEMIN4 |
50628 |
P57678 |
0.63 |
|
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
|
PRR11 |
55771 |
Q96HE9 |
0.63 |
|
EIF1AD |
84285 |
Q8N9N8 |
0.63 |
|
HNRNPU |
3192 |
Q00839 |
0.72 |
|
SUMO2 |
6613 |
P61956 |
0.74 |
|
NOP56 |
10528 |
O00567 |
0.82 |