| Gene Symbol | ST6GAL2 | 
| Entrez ID | 84620 | 
| Uniprot ID | Q96JF0 | 
| Description | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 
| Chromosomal Location | chr2: 106,801,600-106,887,108 | 
| Ontology | GO ID | GO Term | Definition | Evidence | 
|---|---|---|---|---|
| BP | GO:0007275 | multicellular organism development | The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). | NAS | 
| BP | GO:0009311 | oligosaccharide metabolic process | The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. | IDA | 
| BP | GO:0018279 | protein N-linked glycosylation via asparagine | The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification. | IBA | 
| BP | GO:0040007 | growth | The increase in size or mass of an entire organism, a part of an organism or a cell. | NAS | 
| BP | GO:0097503 | sialylation | The covalent attachment of sialic acid to a substrate molecule. | IEA | 
| CC | GO:0000139 | Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. | TAS | 
| CC | GO:0016021 | integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | NAS | 
| CC | GO:0032580 | Golgi cisterna membrane | The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex. | IEA | 
| MF | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity | Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine. | IDA|TAS | 
| Domain ID | Description | 
|---|---|
| IPR001675 | Glycosyl transferase family 29 | 
| IPR011330 | Glycoside hydrolase/deacetylase, beta/alpha-barrel | 
| Pathway ID | Pathway Term | Pathway Source | 
|---|---|---|
| hsa00510 | N-Glycan biosynthesis | KEGG | 
| hsa00514 | Other types of O-glycan biosynthesis | KEGG | 
| hsa01100 | Metabolic pathways | KEGG | 
| WP1424 | Globo Sphingolipid Metabolism | WikiPathways | 
| Pubmed ID | Author | Year | Title | 
|---|---|---|---|
| 22617121 | Ouandaogo et al. | 2012 | Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation | 
| Gene Symbol | Entrez ID | Uniprot ID | Score | 
|---|---|---|---|
| ST6GAL2 | 84620 | Q96JF0 | 0.52 | 
| MCM7 | 4176 | P33993 | 0.63 | 
| CREB3 | 10488 | O43889 | 0.63 |