Gene Symbol | ST6GAL2 |
Entrez ID | 84620 |
Uniprot ID | Q96JF0 |
Description | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 |
Chromosomal Location | chr2: 106,801,600-106,887,108 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007275 |
multicellular organism development |
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). |
NAS |
BP |
GO:0009311 |
oligosaccharide metabolic process |
The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. |
IDA |
BP |
GO:0018279 |
protein N-linked glycosylation via asparagine |
The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification. |
IBA |
BP |
GO:0040007 |
growth |
The increase in size or mass of an entire organism, a part of an organism or a cell. |
NAS |
BP |
GO:0097503 |
sialylation |
The covalent attachment of sialic acid to a substrate molecule. |
IEA |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
TAS |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
NAS |
CC |
GO:0032580 |
Golgi cisterna membrane |
The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex. |
IEA |
MF |
GO:0003835 |
beta-galactoside alpha-2,6-sialyltransferase activity |
Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine. |
IDA|TAS |
Domain ID | Description |
---|---|
IPR001675 |
Glycosyl transferase family 29 |
IPR011330 |
Glycoside hydrolase/deacetylase, beta/alpha-barrel |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00510 |
N-Glycan biosynthesis |
KEGG |
hsa00514 |
Other types of O-glycan biosynthesis |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
WP1424 |
Globo Sphingolipid Metabolism |
WikiPathways |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
ST6GAL2 |
84620 |
Q96JF0 |
0.52 |
MCM7 |
4176 |
P33993 |
0.63 |
CREB3 |
10488 |
O43889 |
0.63 |