Protein Description

Gene Symbol HSDL2
Entrez ID 84263
Uniprot ID Q6YN16
Description hydroxysteroid dehydrogenase like 2
Chromosomal Location chr9: 112,379,937-112,472,410
Ontology GO ID GO Term Definition Evidence

BP

GO:0008150

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

ND

BP

GO:0055114

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

IEA

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IEA

CC

GO:0005777

peroxisome

A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

IDA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

MF

GO:0003674

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

ND

MF

GO:0016491

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

IEA

Domain ID Description

IPR002347

Short-chain dehydrogenase/reductase SDR

IPR003033

SCP2 sterol-binding domain

IPR016040

NAD(P)-binding domain

IPR020904

Short-chain dehydrogenase/reductase, conserved site

No pathways found.

UMLS CUI UMLS Term

C0023903

Liver Neoplasms

Tissue Cell Type

adrenal gland

glandular cells

bone marrow

hematopoietic cells

cerebral cortex

endothelial cells

colon

glandular cells

colon

peripheral nerve/ganglion

duodenum

glandular cells

endometrium

cells in endometrial stroma

endometrium

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

heart muscle

myocytes

hippocampus

glial cells

hippocampus

neuronal cells

kidney

cells in tubules

liver

hepatocytes

lung

macrophages

oral mucosa

squamous epithelial cells

ovary

follicle cells

parathyroid gland

glandular cells

placenta

decidual cells

prostate

glandular cells

rectum

glandular cells

seminal vesicle

glandular cells

skin

epidermal cells

small intestine

glandular cells

stomach

glandular cells

testis

Leydig cells

thyroid gland

glandular cells

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

SF1

7536

Q15637

0.49

TAGLN2

8407

P37802

0.49

TRAP1

10131

Q12931

0.49

DLD

1738

P09622

0.49

NDUFA8

4702

P51970

0.49

NPHP1

4867

O15259

0.49

CNTRL

11064

Q7Z7A1

0.49

RPGRIP1L

23322

Q68CZ1

0.49

TCTN3

26123

Q6NUS6

0.49

ADRB2

154

P07550

0.63

JUN

3725

P05412

0.63

PARK2

5071

O60260

0.63

PEX5

5830

P50542

0.63

SUMO2

6613

P61956

0.63

IKBKE

9641

Q14164

0.63

GABARAP

11337

O95166

0.63

FBXO6

26270

Q9NRD1

0.63

EEF2K

29904

O00418

0.63

HDAC1

3065

Q13547

0.72