| Gene Symbol | ASCC2 |
| Entrez ID | 84164 |
| Uniprot ID | Q9H1I8 |
| Description | activating signal cointegrator 1 complex subunit 2 |
| Chromosomal Location | chr22: 29,788,608-29,838,304 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006307 |
DNA dealkylation involved in DNA repair |
The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT). |
TAS |
|
BP |
GO:0006351 |
transcription, DNA-templated |
The cellular synthesis of RNA on a template of DNA. |
IEA |
|
BP |
GO:0006355 |
regulation of transcription, DNA-templated |
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
IDA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
TAS |
|
CC |
GO:0099053 |
activating signal cointegrator 1 complex |
A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR003892 |
Ubiquitin system component Cue |
|
IPR009060 |
UBA-like |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
lung |
macrophages |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
placenta |
trophoblastic cells |
|
rectum |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
GPC4 |
2239 |
O75487 |
0.49 |
|
UBA1 |
7317 |
P22314 |
0.49 |
|
UBE2N |
7334 |
P61088 |
0.49 |
|
ASCC3 |
10973 |
Q8N3C0 |
0.49 |
|
UBE2V1 |
387522 |
Q13404 |
0.49 |
|
KDM1A |
23028 |
O60341 |
0.63 |
|
FLJ10324 |
N/A |
Q75LH2 |
0.63 |
|
JUN |
3725 |
P05412 |
0.77 |
|
RELA |
5970 |
Q04206 |
0.77 |
|
SRF |
6722 |
P11831 |
0.77 |
|
TRIP4 |
9325 |
Q15650 |
0.77 |
|
RPS19 |
6223 |
P39019 |
0.49 |
|
CC2D2A |
57545 |
Q9P2K1 |
0.49 |
|
CEP128 |
145508 |
Q6ZU80 |
0.49 |
|
MAP3K1 |
4214 |
Q13233 |
0.52 |
|
ENTHD2 |
146705 |
Q96N21 |
0.63 |
|
ASS1 |
445 |
P00966 |
0.63 |
|
GADD45A |
1647 |
P24522 |
0.63 |
|
EEF1D |
1936 |
P29692 |
0.63 |
|
FBP1 |
2203 |
P09467 |
0.63 |
|
GFER |
2671 |
P55789 |
0.63 |
|
GTF3C1 |
2975 |
Q12789 |
0.63 |
|
LPL |
4023 |
P06858 |
0.63 |
|
MYH9 |
4627 |
P35579 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
PIK3CD |
5293 |
O00329 |
0.63 |
|
PIN4 |
5303 |
Q9Y237 |
0.63 |
|
RPA1 |
6117 |
P27694 |
0.63 |
|
RPLP1 |
6176 |
P05386 |
0.63 |
|
SNRPB |
6628 |
P14678 |
0.63 |
|
DEAF1 |
10522 |
O75398 |
0.63 |
|
CKAP4 |
10970 |
Q07065 |
0.63 |
|
FAF1 |
11124 |
Q9UNN5 |
0.63 |
|
SNW1 |
22938 |
Q13573 |
0.63 |
|
POLA2 |
23649 |
Q14181 |
0.63 |
|
POLDIP2 |
26073 |
Q9Y2S7 |
0.63 |
|
GNL3 |
26354 |
Q9BVP2 |
0.63 |
|
RNF11 |
26994 |
Q9Y3C5 |
0.63 |
|
OLA1 |
29789 |
Q9NTK5 |
0.63 |
|
MED31 |
51003 |
Q9Y3C7 |
0.63 |
|
ASCC1 |
51008 |
Q8N9N2 |
0.63 |
|
CUTC |
51076 |
Q9NTM9 |
0.63 |
|
IGSF9 |
57549 |
Q9P2J2 |
0.63 |
|
ELAC2 |
60528 |
Q9BQ52 |
0.63 |
|
PJA1 |
64219 |
Q8NG27 |
0.63 |
|
PAPD5 |
64282 |
Q8NDF8 |
0.63 |
|
FUNDC2 |
65991 |
Q9BWH2 |
0.63 |
|
TBC1D17 |
79735 |
Q9HA65 |
0.63 |
|
URM1 |
81605 |
Q9BTM9 |
0.63 |
|
PCBD2 |
84105 |
Q9H0N5 |
0.63 |
|
ALKBH3 |
221120 |
Q96Q83 |
0.63 |
|
HDAC1 |
3065 |
Q13547 |
0.72 |
|
VCL |
7414 |
P18206 |
0.72 |
|
BAG6 |
7917 |
P46379 |
0.72 |
|
NIPSNAP1 |
8508 |
Q9BPW8 |
0.72 |
|
EMC2 |
9694 |
Q15006 |
0.72 |
|
SPC24 |
147841 |
Q8NBT2 |
0.72 |
|
IMMT |
10989 |
Q16891 |
0.73 |
|
RADIL |
55698 |
Q96JH8 |
0.73 |