Protein Description

Gene Symbol RASSF4
Entrez ID 83937
Uniprot ID Q9H2L5
Description Ras association (RalGDS/AF-6) domain family member 4
Chromosomal Location chr10: 44,959,407-44,995,891
Ontology GO ID GO Term Definition Evidence

BP

GO:0007049

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

IEA

BP

GO:0007165

signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

Domain ID Description

IPR000159

Ras-associating (RA) domain

IPR011524

SARAH domain

IPR029071

Ubiquitin-related domain

IPR033614

C-terminal RASSF family

IPR033622

Ras association domain-containing protein 4

Pathway ID Pathway Term Pathway Source

hsa04392

Hippo signaling pathway -multiple species

KEGG

No diseases found.

Tissue Cell Type

bone marrow

hematopoietic cells

breast

glandular cells

epididymis

glandular cells

fallopian tube

glandular cells

gallbladder

glandular cells

oral mucosa

squamous epithelial cells

seminal vesicle

glandular cells

skin

keratinocytes

small intestine

glandular cells

soft tissue

fibroblasts

soft tissue

peripheral nerve

soft tissue

adipocytes

soft tissue

chondrocytes

stomach

glandular cells

testis

cells in seminiferous ducts

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

HMGB1

3146

P09429

0.52

SAV1

60485

Q9H4B6

0.63

RASSF5

83593

Q8WWW0

0.63

STK3

6788

Q13188

0.89

MAGEA6

4105

P43360

0.63

RASSF3

283349

Q86WH2

0.63

STK4

6789

Q13043

0.89