| Gene Symbol | ANP32E |
| Entrez ID | 81611 |
| Uniprot ID | Q9BTT0 |
| Description | acidic nuclear phosphoprotein 32 family member E |
| Chromosomal Location | chr1: 150,218,417-150,236,156 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006334 |
nucleosome assembly |
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. |
IBA |
|
BP |
GO:0006913 |
nucleocytoplasmic transport |
The directed movement of molecules between the nucleus and the cytoplasm. |
IBA |
|
BP |
GO:0016569 |
chromatin modification |
The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups. |
IEA |
|
BP |
GO:0042981 |
regulation of apoptotic process |
Any process that modulates the occurrence or rate of cell death by apoptotic process. |
IBA |
|
BP |
GO:0043086 |
negative regulation of catalytic activity |
Any process that stops or reduces the activity of an enzyme. |
IEA |
|
BP |
GO:0043486 |
histone exchange |
The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. |
IDA |
|
CC |
GO:0000812 |
Swr1 complex |
A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits. |
IDA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA|ISS |
|
CC |
GO:0016023 |
cytoplasmic, membrane-bounded vesicle |
A membrane-bounded vesicle found in the cytoplasm of the cell. |
ISS |
|
MF |
GO:0019212 |
phosphatase inhibitor activity |
Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. |
IBA|ISS |
|
MF |
GO:0042393 |
histone binding |
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR001611 |
Leucine-rich repeat |
|
IPR032675 |
Leucine-rich repeat domain, L domain-like |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
bone marrow |
hematopoietic cells |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
colon |
peripheral nerve/ganglion |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
soft tissue |
fibroblasts |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
15598877 |
Wood et al. |
2005 |
Valproate-induced alterations in human theca cell gene expression: clues to the association between valproate use and metabolic side effects |
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
PAPPA |
5069 |
Q13219 |
0.49 |
|
RPS2 |
6187 |
P15880 |
0.49 |
|
VPS72 |
6944 |
Q15906 |
0.49 |
|
AHCYL1 |
10768 |
O43865 |
0.49 |
|
AHCYL2 |
23382 |
Q96HN2 |
0.49 |
|
DMAP1 |
55929 |
Q9NPF5 |
0.49 |
|
FOS |
2353 |
P01100 |
0.56 |
|
SMAD2 |
4087 |
Q15796 |
0.56 |
|
SNX2 |
6643 |
O60749 |
0.63 |
|
PLEKHH1 |
57475 |
Q9ULM0 |
0.63 |
|
SNX6 |
58533 |
Q9UNH7 |
0.63 |
|
EWSR1 |
2130 |
Q01844 |
0.49 |
|
NR4A2 |
4929 |
P43354 |
0.49 |
|
TPI1 |
7167 |
P60174 |
0.49 |
|
ANP32A |
8125 |
P39687 |
0.49 |
|
UCHL5 |
51377 |
Q9Y5K5 |
0.56 |
|
ATP6V1C1 |
528 |
P21283 |
0.63 |
|
MGMT |
4255 |
P16455 |
0.63 |
|
RDX |
5962 |
P35241 |
0.63 |
|
SARS |
6301 |
P49591 |
0.63 |
|
SOX2 |
6657 |
P48431 |
0.63 |
|
ATG7 |
10533 |
O95352 |
0.63 |
|
PHLPP1 |
23239 |
O60346 |
0.63 |
|
OTUB1 |
55611 |
Q96FW1 |
0.63 |
|
VPS35 |
55737 |
Q96QK1 |
0.63 |
|
PARD3 |
56288 |
Q8TEW0 |
0.63 |
|
RNASEH2B |
79621 |
Q5TBB1 |
0.63 |
|
FYTTD1 |
84248 |
Q96QD9 |
0.63 |
|
UNK |
85451 |
Q9C0B0 |
0.63 |
|
HIST1H2BA |
255626 |
Q96A08 |
0.63 |
|
KPNA1 |
3836 |
P52294 |
0.72 |
|
MEPCE |
56257 |
Q7L2J0 |
0.72 |
|
UBA5 |
79876 |
Q9GZZ9 |
0.72 |
|
SUMO2 |
6613 |
P61956 |
0.73 |