| Gene Symbol | FIP1L1 |
| Entrez ID | 81608 |
| Uniprot ID | Q6UN15 |
| Description | factor interacting with PAPOLA and CPSF1 |
| Chromosomal Location | chr4: 53,377,643-53,460,861 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0000398 |
mRNA splicing, via spliceosome |
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. |
TAS |
|
BP |
GO:0006369 |
termination of RNA polymerase II transcription |
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed. |
TAS |
|
BP |
GO:0006406 |
mRNA export from nucleus |
The directed movement of mRNA from the nucleus to the cytoplasm. |
TAS |
|
BP |
GO:0031124 |
mRNA 3'-end processing |
Any process involved in forming the mature 3' end of an mRNA molecule. |
TAS |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA|TAS |
|
CC |
GO:0005847 |
mRNA cleavage and polyadenylation specificity factor complex |
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal. |
IEA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR007854 |
Pre-mRNA polyadenylation factor Fip1 |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa03015 |
mRNA surveillance pathway |
KEGG |
| UMLS CUI | UMLS Term |
|---|---|
|
C0023487 |
Acute Promyelocytic Leukemia |
|
C1540912 |
Hypereosinophilic Syndrome |
| Tissue | Cell Type |
|---|---|
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
neuronal cells |
|
colon |
glandular cells |
|
colon |
peripheral nerve/ganglion |
|
duodenum |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in tubules |
|
nasopharynx |
respiratory epithelial cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
rectum |
glandular cells |
|
skin |
epidermal cells |
|
testis |
cells in seminiferous ducts |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
12734205 |
Wood et al. |
2003 |
The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis |
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
FOS |
2353 |
P01100 |
0.49 |
|
NUP153 |
9972 |
P49790 |
0.49 |
|
PCF11 |
51585 |
O94913 |
0.49 |
|
APP |
351 |
P05067 |
0.56 |
|
PAPOLA |
10914 |
P51003 |
0.56 |
|
ZMYND19 |
116225 |
Q96E35 |
0.63 |
|
CSTF1 |
1477 |
Q05048 |
0.72 |
|
CSTF2 |
1478 |
P33240 |
0.72 |
|
PRMT2 |
3275 |
P55345 |
0.72 |
|
LSS |
4047 |
P48449 |
0.72 |
|
P4HA1 |
5033 |
P13674 |
0.72 |
|
P4HB |
5034 |
P07237 |
0.72 |
|
PML |
5371 |
P29590 |
0.72 |
|
SYMPK |
8189 |
Q92797 |
0.72 |
|
P4HA2 |
8974 |
O15460 |
0.72 |
|
CRTAP |
10491 |
O75718 |
0.72 |
|
WWP2 |
11060 |
O00308 |
0.72 |
|
CSTF2T |
23283 |
Q9H0L4 |
0.82 |
|
WDR33 |
55339 |
Q9C0J8 |
0.82 |
|
CSTF3 |
1479 |
Q12996 |
0.84 |
|
HIST1H1C |
3006 |
P16403 |
0.49 |
|
SRPK2 |
6733 |
P78362 |
0.52 |
|
ESR1 |
2099 |
P03372 |
0.63 |
|
ESR2 |
2100 |
Q92731 |
0.63 |
|
EZH2 |
2146 |
Q15910 |
0.63 |
|
GOLGA2 |
2801 |
Q08379 |
0.63 |
|
GSK3B |
2932 |
P49841 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
LIG4 |
3981 |
P49917 |
0.63 |
|
MCM7 |
4176 |
P33993 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
RNF2 |
6045 |
Q99496 |
0.63 |
|
SGTA |
6449 |
O43765 |
0.63 |
|
STAU1 |
6780 |
O95793 |
0.63 |
|
TFAP2C |
7022 |
Q92754 |
0.63 |
|
XPO1 |
7514 |
O14980 |
0.63 |
|
NAA10 |
8260 |
P41227 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
CUL7 |
9820 |
Q14999 |
0.63 |
|
PTBP3 |
9991 |
O95758 |
0.63 |
|
COPS5 |
10987 |
Q92905 |
0.63 |
|
SNW1 |
22938 |
Q13573 |
0.63 |
|
OBSL1 |
23363 |
O75147 |
0.63 |
|
SUZ12 |
23512 |
Q15022 |
0.63 |
|
SRRM2 |
23524 |
Q9UQ35 |
0.63 |
|
MED4 |
29079 |
Q9NPJ6 |
0.63 |
|
DDX41 |
51428 |
Q9UJV9 |
0.63 |
|
EAF1 |
85403 |
Q96JC9 |
0.63 |
|
CPSF4L |
642843 |
A6NMK7 |
0.63 |
|
HNRNPA1 |
3178 |
P09651 |
0.68 |
|
CSNK2A1 |
1457 |
P68400 |
0.70 |
|
FOXL2 |
668 |
P58012 |
0.72 |
|
CLK2 |
1196 |
P49760 |
0.72 |
|
KIF2A |
3796 |
O00139 |
0.72 |
|
LLGL2 |
3993 |
Q6P1M3 |
0.72 |
|
HDAC9 |
9734 |
Q9UKV0 |
0.72 |
|
SEC16A |
9919 |
O15027 |
0.72 |
|
POLK |
51426 |
Q9UBT6 |
0.72 |
|
PRMT6 |
55170 |
Q96LA8 |
0.72 |
|
KIF21A |
55605 |
Q7Z4S6 |
0.72 |
|
CDCA5 |
113130 |
Q96FF9 |
0.72 |
|
CEP170P1 |
645455 |
Q96L14 |
0.72 |
|
WWOX |
51741 |
Q9NZC7 |
0.78 |
|
CPSF3 |
51692 |
Q9UKF6 |
0.83 |
|
CPSF2 |
53981 |
Q9P2I0 |
0.83 |
|
CPSF1 |
29894 |
Q10570 |
0.85 |
|
CPSF4 |
10898 |
O95639 |
0.88 |