Protein Description

Gene Symbol ZFP91
Entrez ID 80829
Uniprot ID Q96JP5
Description ZFP91 zinc finger protein
Chromosomal Location chr11: 58,579,111-58,621,042
Ontology GO ID GO Term Definition Evidence

BP

GO:0007250

activation of NF-kappaB-inducing kinase activity

The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.

IDA

BP

GO:0070534

protein K63-linked ubiquitination

A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.

IDA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IEA

MF

GO:0003676

nucleic acid binding

Interacting selectively and non-covalently with any nucleic acid.

IEA

MF

GO:0004842

ubiquitin-protein transferase activity

Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.

IDA

MF

GO:0016874

ligase activity

Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

IEA

MF

GO:0046872

metal ion binding

Interacting selectively and non-covalently with any metal ion.

IEA

Domain ID Description

IPR013083

Zinc finger, RING/FYVE/PHD-type

IPR013087

Zinc finger C2H2-type

No pathways found.

UMLS CUI UMLS Term

C0024299

Lymphoma

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

bone marrow

hematopoietic cells

breast

glandular cells

breast

myoepithelial cells

bronchus

respiratory epithelial cells

caudate

glial cells

caudate

neuronal cells

cerebellum

cells in granular layer

cerebellum

cells in molecular layer

cerebral cortex

endothelial cells

cerebral cortex

glial cells

cerebral cortex

neuronal cells

cervix, uterine

glandular cells

colon

endothelial cells

colon

glandular cells

duodenum

glandular cells

endometrium

cells in endometrial stroma

endometrium

glandular cells

epididymis

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

heart muscle

myocytes

hippocampus

glial cells

hippocampus

neuronal cells

kidney

cells in glomeruli

kidney

cells in tubules

liver

bile duct cells

liver

hepatocytes

lung

macrophages

lung

pneumocytes

nasopharynx

respiratory epithelial cells

oral mucosa

squamous epithelial cells

ovary

ovarian stroma cells

pancreas

exocrine glandular cells

parathyroid gland

glandular cells

placenta

trophoblastic cells

prostate

glandular cells

rectum

glandular cells

salivary gland

glandular cells

seminal vesicle

glandular cells

skin

fibroblasts

skin

keratinocytes

skin

Langerhans

skin

melanocytes

skin

epidermal cells

smooth muscle

smooth muscle cells

soft tissue

adipocytes

soft tissue

fibroblasts

soft tissue

peripheral nerve

spleen

cells in red pulp

spleen

cells in white pulp

stomach

glandular cells

testis

cells in seminiferous ducts

tonsil

germinal center cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

17148555

Wood et al.

2007

Molecular Abnormalities in Oocytes from Women with Polycystic Ovary Syndrome Revealed by Microarray Analysis

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

FOS

2353

P01100

0.49

MAP3K14

9020

Q99558

0.70

CENPA

1058

P49450

0.49

USP5

8078

P45974

0.49

HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI

8339

P62807

0.49

UTP20

27340

O75691

0.49

SRPK2

6733

P78362

0.52

ESR2

2100

Q92731

0.55

CASQ2

845

O14958

0.63

ELAVL1

1994

Q15717

0.63

FBL

2091

P22087

0.63

RNF2

6045

Q99496

0.63

SUMO2

6613

P61956

0.63

SUMO1

7341

P63165

0.63

RNPS1

10921

Q15287

0.63

LUC7L

55692

Q9NQ29

0.63

CDKN2A

1029

P42771

0.65

DLG3

1741

Q92796

0.72

GBA

2629

P04062

0.72

PAEP

5047

P09466

0.72

CTR9

9646

Q6PD62

0.72

FTSJ1

24140

Q9UET6

0.72