BP

GO:0007275

multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

IEA

BP

GO:0007596

blood coagulation

The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

IBA

BP

GO:0008284

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

IBA

BP

GO:0014068

positive regulation of phosphatidylinositol 3-kinase signaling

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.

IBA

BP

GO:0030335

positive regulation of cell migration

Any process that activates or increases the frequency, rate or extent of cell migration.

IBA

BP

GO:0031954

positive regulation of protein autophosphorylation

Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.

IBA

BP

GO:0036120

cellular response to platelet-derived growth factor stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.

IEA

BP

GO:0043406

positive regulation of MAP kinase activity

Any process that activates or increases the frequency, rate or extent of MAP kinase activity.

IBA

BP

GO:0048008

platelet-derived growth factor receptor signaling pathway

The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands.

IBA

BP

GO:0048146

positive regulation of fibroblast proliferation

Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.

IEA

BP

GO:0048661

positive regulation of smooth muscle cell proliferation

Any process that activates or increases the rate or extent of smooth muscle cell proliferation.

IEA

BP

GO:0050730

regulation of peptidyl-tyrosine phosphorylation

Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.

IEA

BP

GO:0051781

positive regulation of cell division

Any process that activates or increases the frequency, rate or extent of cell division.

IEA

BP

GO:0070301

cellular response to hydrogen peroxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

IEA

BP

GO:0070374

positive regulation of ERK1 and ERK2 cascade

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

IBA

BP

GO:0071230

cellular response to amino acid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.

IEA

BP

GO:0071560

cellular response to transforming growth factor beta stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.

IEA

BP

GO:0071673

positive regulation of smooth muscle cell chemotaxis

Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.

IEA

BP

GO:0072126

positive regulation of glomerular mesangial cell proliferation

Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.

IEA

BP

GO:2000439

positive regulation of monocyte extravasation

Any process that activates or increases the frequency, rate or extent of monocyte extravasation.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0005576

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

TAS

CC

GO:0005615

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

IBA

CC

GO:0005788

endoplasmic reticulum lumen

The volume enclosed by the membranes of the endoplasmic reticulum.

TAS

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0005161

platelet-derived growth factor receptor binding

Interacting selectively and non-covalently with the platelet-derived growth factor receptor.

IBA

MF

GO:0008083

growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.

IEA