BP

GO:0031087

deadenylation-independent decapping of nuclear-transcribed mRNA

Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening.

IBA

BP

GO:0033962

cytoplasmic mRNA processing body assembly

The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.

IBA

BP

GO:0043928

exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay

The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail.

TAS

BP

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.

IEA

CC

GO:0000932

cytoplasmic mRNA processing body

A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized to these foci.

IBA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

MF

GO:0003729

mRNA binding

Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.

IBA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0042802

identical protein binding

Interacting selectively and non-covalently with an identical protein or proteins.

IPI

MF

GO:1990174

phosphodiesterase decapping endonuclease activity

Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA.

IMP