Protein Description

Gene Symbol ERMP1
Entrez ID 79956
Uniprot ID Q7Z2K6
Description endoplasmic reticulum metallopeptidase 1
Chromosomal Location chr9: 5,765,076-5,833,117
Ontology GO ID GO Term Definition Evidence

BP

GO:0006508

proteolysis

The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

IEA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IEA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

MF

GO:0008237

metallopeptidase activity

Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

IEA

MF

GO:0046872

metal ion binding

Interacting selectively and non-covalently with any metal ion.

IEA

Domain ID Description

IPR007484

Peptidase M28

No pathways found.

No diseases found.

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

breast

glandular cells

bronchus

respiratory epithelial cells

caudate

neuronal cells

cervix, uterine

squamous epithelial cells

colon

endothelial cells

endometrium

glandular cells

esophagus

squamous epithelial cells

gallbladder

glandular cells

kidney

cells in tubules

nasopharynx

respiratory epithelial cells

parathyroid gland

glandular cells

placenta

decidual cells

placenta

trophoblastic cells

rectum

glandular cells

skeletal muscle

myocytes

skin

keratinocytes

skin

epidermal cells

thyroid gland

glandular cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

TM9SF4

9777

Q92544

0.49

ELAVL1

1994

Q15717

0.63

GABRE

2564

P78334

0.63

GPM6A

2823

P51674

0.63

SUMO1

7341

P63165

0.63

GPR52

9293

Q9Y2T5

0.63

UBD

10537

O15205

0.63

CA14

23632

Q9ULX7

0.63

MCOLN3

55283

Q8TDD5

0.63

HTR3C

170572

Q8WXA8

0.63

ZACN

353174

Q401N2

0.63

C4orf3

401152

Q8WVX3

0.63

STAT5A

6776

P42229

0.72

YWHAH

7533

Q04917

0.72