Gene Symbol | ERMP1 |
Entrez ID | 79956 |
Uniprot ID | Q7Z2K6 |
Description | endoplasmic reticulum metallopeptidase 1 |
Chromosomal Location | chr9: 5,765,076-5,833,117 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006508 |
proteolysis |
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
IEA |
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
IEA |
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
MF |
GO:0008237 |
metallopeptidase activity |
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
IEA |
MF |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
Domain ID | Description |
---|---|
IPR007484 |
Peptidase M28 |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
breast |
glandular cells |
bronchus |
respiratory epithelial cells |
caudate |
neuronal cells |
cervix, uterine |
squamous epithelial cells |
colon |
endothelial cells |
endometrium |
glandular cells |
esophagus |
squamous epithelial cells |
gallbladder |
glandular cells |
kidney |
cells in tubules |
nasopharynx |
respiratory epithelial cells |
parathyroid gland |
glandular cells |
placenta |
decidual cells |
placenta |
trophoblastic cells |
rectum |
glandular cells |
skeletal muscle |
myocytes |
skin |
keratinocytes |
skin |
epidermal cells |
thyroid gland |
glandular cells |
tonsil |
squamous epithelial cells |
urinary bladder |
urothelial cells |
vagina |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
TM9SF4 |
9777 |
Q92544 |
0.49 |
ELAVL1 |
1994 |
Q15717 |
0.63 |
GABRE |
2564 |
P78334 |
0.63 |
GPM6A |
2823 |
P51674 |
0.63 |
SUMO1 |
7341 |
P63165 |
0.63 |
GPR52 |
9293 |
Q9Y2T5 |
0.63 |
UBD |
10537 |
O15205 |
0.63 |
CA14 |
23632 |
Q9ULX7 |
0.63 |
MCOLN3 |
55283 |
Q8TDD5 |
0.63 |
HTR3C |
170572 |
Q8WXA8 |
0.63 |
ZACN |
353174 |
Q401N2 |
0.63 |
C4orf3 |
401152 |
Q8WVX3 |
0.63 |
STAT5A |
6776 |
P42229 |
0.72 |
YWHAH |
7533 |
Q04917 |
0.72 |