Protein Description

Gene Symbol NAA60
Entrez ID 79903
Uniprot ID Q9H7X0
Description N(alpha)-acetyltransferase 60, NatF catalytic subunit
Chromosomal Location chr16: 3,443,611-3,486,963
Ontology GO ID GO Term Definition Evidence

BP

GO:0006334

nucleosome assembly

The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.

IDA

BP

GO:0007059

chromosome segregation

The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

IBA|ISS

BP

GO:0008283

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

IMP

BP

GO:0017196

N-terminal peptidyl-methionine acetylation

The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.

IDA

BP

GO:0043967

histone H4 acetylation

The modification of histone H4 by the addition of an acetyl group.

IDA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IDA

MF

GO:0004596

peptide alpha-N-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein.

IDA

MF

GO:0010485

H4 histone acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.

IDA

Domain ID Description

IPR000182

GNAT domain

IPR016181

Acyl-CoA N-acyltransferase

No pathways found.

No diseases found.

Tissue Cell Type

cerebral cortex

neuropil

gallbladder

glandular cells

hippocampus

neuronal cells

testis

Leydig cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

No partners found.