Protein Description

Gene Symbol SNRNP25
Entrez ID 79622
Uniprot ID Q9BV90
Description small nuclear ribonucleoprotein, U11/U12 25kDa subunit
Chromosomal Location chr16: 53,010-57,669
Ontology GO ID GO Term Definition Evidence

BP

GO:0000398

mRNA splicing, via spliceosome

The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

TAS

BP

GO:0008380

RNA splicing

The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

IC

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA|TAS

CC

GO:0005689

U12-type spliceosomal complex

Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site.

IDA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA

CC

GO:0045171

intercellular bridge

A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

Domain ID Description

IPR000626

Ubiquitin domain

IPR029071

Ubiquitin-related domain

No pathways found.

No diseases found.

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

bone marrow

hematopoietic cells

cerebellum

cells in granular layer

cerebellum

Purkinje cells

cervix, uterine

glandular cells

colon

glandular cells

duodenum

glandular cells

gallbladder

glandular cells

heart muscle

myocytes

kidney

cells in tubules

liver

hepatocytes

lung

macrophages

pancreas

islets of Langerhans

placenta

decidual cells

placenta

trophoblastic cells

rectum

glandular cells

skin

epidermal cells

small intestine

glandular cells

smooth muscle

smooth muscle cells

stomach

glandular cells

testis

Leydig cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

CPSF7

79869

Q8N684

0.63

EFHC2

80258

Q5JST6

0.63

LNX1

84708

Q8TBB1

0.63

LHX4

89884

Q969G2

0.63

ENO1

2023

P06733

0.63

KRT31

3881

Q15323

0.63

MOV10

4343

Q9HCE1

0.63

REL

5966

Q04864

0.63

TRAF2

7186

Q12933

0.63

NXF1

10482

Q9UBU9

0.63

C11orf57

55216

Q6ZUT1

0.63

RNU12

267010

N/A

0.63

RNU12-2P

26823

N/A

0.72

RNU11

26824

N/A

0.72