Protein Description

Gene Symbol DCTPP1
Entrez ID 79077
Uniprot ID Q9H773
Description dCTP pyrophosphatase 1
Chromosomal Location chr16: 30,423,619-30,430,075
Ontology GO ID GO Term Definition Evidence

BP

GO:0009143

nucleoside triphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.

ISS

BP

GO:0051289

protein homotetramerization

The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.

IEA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

ISS

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

ISS

MF

GO:0032556

pyrimidine deoxyribonucleotide binding

Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.

IEA

MF

GO:0042802

identical protein binding

Interacting selectively and non-covalently with an identical protein or proteins.

IPI

MF

GO:0047429

nucleoside-triphosphate diphosphatase activity

Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.

ISS

MF

GO:0047840

dCTP diphosphatase activity

Catalysis of the reaction: dCTP + H2O = dCMP + diphosphate.

IEA

Domain ID Description

IPR009039

EAR

IPR025984

dCTP pyrophosphatase 1

Pathway ID Pathway Term Pathway Source

hsa00240

Pyrimidine metabolism

KEGG

hsa01100

Metabolic pathways

KEGG

No diseases found.

Tissue Cell Type

appendix

glandular cells

endometrium

glandular cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

NOA1

84273

Q8NC60

0.49

APP

351

P05067

0.56

CAPZB

832

P47756

0.63

RAD23A

5886

P54725

0.63

GNPDA1

10007

P46926

0.63

WDR4

10785

P57081

0.63

HERC4

26091

Q5GLZ8

0.63

PDE12

201626

Q6L8Q7

0.63

DCTPP1

79077

Q9H773

0.80

CIAPIN1

57019

Q6FI81

0.49

CRY2

1408

Q49AN0

0.63

CTPS1

1503

P17812

0.63

HLA-B

3106

P30480

0.63

NUBP1

4682

P53384

0.63

NEDD8

4738

Q15843

0.63

PCNA

5111

P12004

0.63

SDCBP

6386

O00560

0.63

VHL

7428

P40337

0.63

XPNPEP1

7511

Q9NQW7

0.63

CUL5

8065

Q93034

0.63

NXF1

10482

Q9UBU9

0.63

UBQLN1

29979

Q9UMX0

0.63

WWOX

51741

Q9NZC7

0.63

CHMP4B

128866

Q9H444

0.72

WDYHV1

55093

Q96HA8

0.73

NIF3L1

60491

Q9GZT8

0.73

PLK1

5347

P53350

0.76