BP

GO:0006886

intracellular protein transport

The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

IEA

BP

GO:0007368

determination of left/right symmetry

The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.

IEA

BP

GO:0007507

heart development

The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.

IEA

BP

GO:0016192

vesicle-mediated transport

A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.

IEA

BP

GO:0019886

antigen processing and presentation of exogenous peptide antigen via MHC class II

The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.

TAS

BP

GO:0050690

regulation of defense response to virus by virus

Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism.

TAS

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0005765

lysosomal membrane

The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.

TAS

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

CC

GO:0030131

clathrin adaptor complex

A membrane coat adaptor complex that links clathrin to a membrane.

IEA

CC

GO:0030659

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

TAS

CC

GO:0030669

clathrin-coated endocytic vesicle membrane

The lipid bilayer surrounding a clathrin-coated endocytic vesicle.

TAS

CC

GO:0032588

trans-Golgi network membrane

The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.

TAS

MF

GO:0005215

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.

TAS

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0008565

protein transporter activity

Enables the directed movement of proteins into, out of or within a cell, or between cells.

IEA

MF

GO:0019901

protein kinase binding

Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.

ISS