BP

GO:0002028

regulation of sodium ion transport

Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

ISS

BP

GO:0003084

positive regulation of systemic arterial blood pressure

The process that increases the force with which blood travels through the systemic arterial circulatory system.

IEA

BP

GO:0006468

protein phosphorylation

The process of introducing a phosphate group on to a protein.

IDA|IMP

BP

GO:0006811

ion transport

The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

ISS

BP

GO:0010923

negative regulation of phosphatase activity

Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.

IDA

BP

GO:0018107

peptidyl-threonine phosphorylation

The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.

TAS

BP

GO:0023016

signal transduction by trans-phosphorylation

A process in which the transfer of one or more phosphate groups by a kinase to a residue in a different protein molecule transmits a signal.

IDA

BP

GO:0032147

activation of protein kinase activity

Any process that initiates the activity of an inactive protein kinase.

IEA

BP

GO:0032414

positive regulation of ion transmembrane transporter activity

Any process that activates or increases the activity of an ion transporter.

IBA

BP

GO:0035556

intracellular signal transduction

The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

IDA|TAS

BP

GO:0046777

protein autophosphorylation

The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).

IEA

BP

GO:0048666

neuron development

The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

NAS

BP

GO:0050794

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

ISS

BP

GO:0071901

negative regulation of protein serine/threonine kinase activity

Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity.

IEA

BP

GO:0090188

negative regulation of pancreatic juice secretion

Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.

IEA

BP

GO:2000021

regulation of ion homeostasis

Any process that modulates the frequency, rate or extent of ion homeostasis.

IBA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IBA|ISS

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

ISS

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

IEA

MF

GO:0004672

protein kinase activity

Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.

IMP

MF

GO:0004674

protein serine/threonine kinase activity

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

IDA|TAS

MF

GO:0005524

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

IDA

MF

GO:0019869

chloride channel inhibitor activity

Stops, prevents, or reduces the activity of a chloride channel.

IDA

MF

GO:0019870

potassium channel inhibitor activity

Stops, prevents, or reduces the activity of a potassium channel.

IEA

MF

GO:0019901

protein kinase binding

Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.

IPI

MF

GO:0019902

phosphatase binding

Interacting selectively and non-covalently with any phosphatase.

IDA

MF

GO:0030291

protein serine/threonine kinase inhibitor activity

Stops, prevents or reduces the activity of a protein serine/threonine kinase.

IEA

MF

GO:0030295

protein kinase activator activity

Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.

IMP