Protein Description

Gene Symbol PLPPR2
Entrez ID 64748
Uniprot ID Q96GM1
Description phospholipid phosphatase related 2
Chromosomal Location chr19: 11,355,386-11,365,698
Ontology GO ID GO Term Definition Evidence

BP

GO:0006644

phospholipid metabolic process

The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.

IBA

BP

GO:0007165

signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

IBA

BP

GO:0046839

phospholipid dephosphorylation

The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.

IBA

CC

GO:0005887

integral component of plasma membrane

The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IBA

MF

GO:0008195

phosphatidate phosphatase activity

Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.

IEA

MF

GO:0042577

lipid phosphatase activity

Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.

IBA

Domain ID Description

IPR000326

Phosphatidic acid phosphatase type 2/haloperoxidase

IPR028679

Lipid phosphate phosphatase-related protein type 2

No pathways found.

No diseases found.

Tissue Cell Type

liver

hepatocytes

No databases found.

Pubmed ID Author Year Title

26459919

Lan et al.

2015

Functional microarray analysis of differentially expressed genes in granulosa cells from women with polycystic ovary syndrome related to MAPK/ERK signaling

Gene Symbol Entrez ID Uniprot ID Score

ARF5

381

P84085

0.63

PCDH9

5101

Q9HC56

0.63

TUBG1

7283

P23258

0.63

SEC24D

9871

O94855

0.63

ANAPC10

10393

Q9UM13

0.63

METAP2

10988

P50579

0.63

METAP1

23173

P53582

0.63

NME7

29922

Q9Y5B8

0.63

EPN1

29924

Q9Y6I3

0.63

SAR1B

51128

Q9Y6B6

0.63

YTHDF1

54915

Q9BYJ9

0.63

C9orf40

55071

Q8IXQ3

0.63

DNAJC12

56521

Q9UKB3

0.63

DSCC1

79075

Q9BVC3

0.63

ZNF703

80139

Q9H7S9

0.63

ISCA1

81689

Q9BUE6

0.63

UQCC2

84300

Q9BRT2

0.63

WDR73

84942

Q6P4I2

0.63

DPP9

91039

Q86TI2

0.63

TTC5

91875

Q8N0Z6

0.63

SPC24

147841

Q8NBT2

0.63

RNF214

257160

Q8ND24

0.63