Gene Symbol | PLPPR2 |
Entrez ID | 64748 |
Uniprot ID | Q96GM1 |
Description | phospholipid phosphatase related 2 |
Chromosomal Location | chr19: 11,355,386-11,365,698 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006644 |
phospholipid metabolic process |
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester. |
IBA |
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
IBA |
BP |
GO:0046839 |
phospholipid dephosphorylation |
The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents. |
IBA |
CC |
GO:0005887 |
integral component of plasma membrane |
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IBA |
MF |
GO:0008195 |
phosphatidate phosphatase activity |
Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate. |
IEA |
MF |
GO:0042577 |
lipid phosphatase activity |
Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate. |
IBA |
Domain ID | Description |
---|---|
IPR000326 |
Phosphatidic acid phosphatase type 2/haloperoxidase |
IPR028679 |
Lipid phosphate phosphatase-related protein type 2 |
Tissue | Cell Type |
---|---|
liver |
hepatocytes |
Pubmed ID | Author | Year | Title |
---|---|---|---|
26459919 |
Lan et al. |
2015 |
Functional microarray analysis of differentially expressed genes in granulosa cells from women with polycystic ovary syndrome related to MAPK/ERK signaling |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
ARF5 |
381 |
P84085 |
0.63 |
PCDH9 |
5101 |
Q9HC56 |
0.63 |
TUBG1 |
7283 |
P23258 |
0.63 |
SEC24D |
9871 |
O94855 |
0.63 |
ANAPC10 |
10393 |
Q9UM13 |
0.63 |
METAP2 |
10988 |
P50579 |
0.63 |
METAP1 |
23173 |
P53582 |
0.63 |
NME7 |
29922 |
Q9Y5B8 |
0.63 |
EPN1 |
29924 |
Q9Y6I3 |
0.63 |
SAR1B |
51128 |
Q9Y6B6 |
0.63 |
YTHDF1 |
54915 |
Q9BYJ9 |
0.63 |
C9orf40 |
55071 |
Q8IXQ3 |
0.63 |
DNAJC12 |
56521 |
Q9UKB3 |
0.63 |
DSCC1 |
79075 |
Q9BVC3 |
0.63 |
ZNF703 |
80139 |
Q9H7S9 |
0.63 |
ISCA1 |
81689 |
Q9BUE6 |
0.63 |
UQCC2 |
84300 |
Q9BRT2 |
0.63 |
WDR73 |
84942 |
Q6P4I2 |
0.63 |
DPP9 |
91039 |
Q86TI2 |
0.63 |
TTC5 |
91875 |
Q8N0Z6 |
0.63 |
SPC24 |
147841 |
Q8NBT2 |
0.63 |
RNF214 |
257160 |
Q8ND24 |
0.63 |