Protein Description

Gene Symbol ACBD3
Entrez ID 64746
Uniprot ID Q9H3P7
Description acyl-CoA binding domain containing 3
Chromosomal Location chr1: 226,144,679-226,186,730
Ontology GO ID GO Term Definition Evidence

BP

GO:0006694

steroid biosynthetic process

The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.

IEA

BP

GO:0006810

transport

The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IEA

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IEA

CC

GO:0005794

Golgi apparatus

A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.

IDA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

MF

GO:0000062

fatty-acyl-CoA binding

Interacting selectively and non-covalently with acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0034237

protein kinase A regulatory subunit binding

Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A.

IPI

Domain ID Description

IPR000582

Acyl-CoA-binding protein, ACBP

IPR009038

GOLD domain

IPR014352

FERM/acyl-CoA-binding protein, 3-helical bundle

IPR022408

Acyl-CoA-binding protein, ACBP, conserved site

No pathways found.

No diseases found.

Tissue Cell Type

appendix

glandular cells

bone marrow

hematopoietic cells

cerebral cortex

neuronal cells

colon

glandular cells

duodenum

glandular cells

gallbladder

glandular cells

hippocampus

neuronal cells

pancreas

exocrine glandular cells

placenta

decidual cells

placenta

trophoblastic cells

prostate

glandular cells

small intestine

glandular cells

No databases found.

Pubmed ID Author Year Title

19141487

Kenigsberg et al.

2009

Gene expression microarray profiles of cumulus cells in lean and overweightobese polycystic ovary syndrome patients

Gene Symbol Entrez ID Uniprot ID Score

TGOLN2

10618

O43493

0.03

PI4KB

5298

Q9UBF8

0.24

HARS

3035

P12081

0.63

SARS

6301

P49591

0.63

TBCD

6904

Q9BTW9

0.63

EFTUD2

9343

Q15029

0.63

SNF8

11267

Q96H20

0.63

RPUSD2

27079

Q8IZ73

0.63

VPS36

51028

Q86VN1

0.63

WDR12

55759

Q9GZL7

0.63

UNC45A

55898

Q9H3U1

0.63

DUS3L

56931

Q96G46

0.63

GOLGB1

2804

Q14789

0.73

PKN2

5586

Q16513

0.49

SRSF2

6427

Q01130

0.49

TMEM216

51259

Q9P0N5

0.49

KDM2B

84678

Q8NHM5

0.49

NUP35

129401

Q8NFH5

0.49

EVC2

132884

Q86UK5

0.49

TMEM17

200728

Q86X19

0.49

GOLGA3

2802

Q08378

0.56

ELAVL1

1994

Q15717

0.63

GTF2E1

2960

P29083

0.63

NTRK1

4914

P04629

0.63

SUMO2

6613

P61956

0.63

PPIE

10450

Q9UNP9

0.63

SLC35A1

10559

P78382

0.63

TBC1D22A

25771

Q8WUA7

0.63

GORASP2

26003

Q9H8Y8

0.63

SMURF2

64750

Q9HAU4

0.63

CUL3

8452

Q13618

0.73