Gene Symbol | ACBD3 |
Entrez ID | 64746 |
Uniprot ID | Q9H3P7 |
Description | acyl-CoA binding domain containing 3 |
Chromosomal Location | chr1: 226,144,679-226,186,730 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006694 |
steroid biosynthetic process |
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. |
IEA |
BP |
GO:0006810 |
transport |
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. |
IEA |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
IEA |
CC |
GO:0005739 |
mitochondrion |
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
IEA |
CC |
GO:0005794 |
Golgi apparatus |
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions. |
IDA |
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
MF |
GO:0000062 |
fatty-acyl-CoA binding |
Interacting selectively and non-covalently with acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group. |
IEA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0034237 |
protein kinase A regulatory subunit binding |
Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A. |
IPI |
Domain ID | Description |
---|---|
IPR000582 |
Acyl-CoA-binding protein, ACBP |
IPR009038 |
GOLD domain |
IPR014352 |
FERM/acyl-CoA-binding protein, 3-helical bundle |
IPR022408 |
Acyl-CoA-binding protein, ACBP, conserved site |
Tissue | Cell Type |
---|---|
appendix |
glandular cells |
bone marrow |
hematopoietic cells |
cerebral cortex |
neuronal cells |
colon |
glandular cells |
duodenum |
glandular cells |
gallbladder |
glandular cells |
hippocampus |
neuronal cells |
pancreas |
exocrine glandular cells |
placenta |
decidual cells |
placenta |
trophoblastic cells |
prostate |
glandular cells |
small intestine |
glandular cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
19141487 |
Kenigsberg et al. |
2009 |
Gene expression microarray profiles of cumulus cells in lean and overweightobese polycystic ovary syndrome patients |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
TGOLN2 |
10618 |
O43493 |
0.03 |
PI4KB |
5298 |
Q9UBF8 |
0.24 |
HARS |
3035 |
P12081 |
0.63 |
SARS |
6301 |
P49591 |
0.63 |
TBCD |
6904 |
Q9BTW9 |
0.63 |
EFTUD2 |
9343 |
Q15029 |
0.63 |
SNF8 |
11267 |
Q96H20 |
0.63 |
RPUSD2 |
27079 |
Q8IZ73 |
0.63 |
VPS36 |
51028 |
Q86VN1 |
0.63 |
WDR12 |
55759 |
Q9GZL7 |
0.63 |
UNC45A |
55898 |
Q9H3U1 |
0.63 |
DUS3L |
56931 |
Q96G46 |
0.63 |
GOLGB1 |
2804 |
Q14789 |
0.73 |
PKN2 |
5586 |
Q16513 |
0.49 |
SRSF2 |
6427 |
Q01130 |
0.49 |
TMEM216 |
51259 |
Q9P0N5 |
0.49 |
KDM2B |
84678 |
Q8NHM5 |
0.49 |
NUP35 |
129401 |
Q8NFH5 |
0.49 |
EVC2 |
132884 |
Q86UK5 |
0.49 |
TMEM17 |
200728 |
Q86X19 |
0.49 |
GOLGA3 |
2802 |
Q08378 |
0.56 |
ELAVL1 |
1994 |
Q15717 |
0.63 |
GTF2E1 |
2960 |
P29083 |
0.63 |
NTRK1 |
4914 |
P04629 |
0.63 |
SUMO2 |
6613 |
P61956 |
0.63 |
PPIE |
10450 |
Q9UNP9 |
0.63 |
SLC35A1 |
10559 |
P78382 |
0.63 |
TBC1D22A |
25771 |
Q8WUA7 |
0.63 |
GORASP2 |
26003 |
Q9H8Y8 |
0.63 |
SMURF2 |
64750 |
Q9HAU4 |
0.63 |
CUL3 |
8452 |
Q13618 |
0.73 |