Protein Description

Gene Symbol GMCL1
Entrez ID 64395
Uniprot ID Q96IK5
Description germ cell-less, spermatogenesis associated 1
Chromosomal Location chr2: 69,829,642-69,881,396
Ontology GO ID GO Term Definition Evidence

BP

GO:0006355

regulation of transcription, DNA-templated

Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

IEA

BP

GO:0007275

multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

IEA

BP

GO:0007283

spermatogenesis

The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.

IEA

BP

GO:0030154

cell differentiation

The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

IEA

CC

GO:0000151

ubiquitin ligase complex

A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.

IBA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IBA

CC

GO:0005635

nuclear envelope

The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).

IEA

CC

GO:0016363

nuclear matrix

The dense fibrillar network lying on the inner side of the nuclear membrane.

IEA

Domain ID Description

IPR000210

BTB/POZ domain

IPR011333

SKP1/BTB/POZ domain

IPR011705

BTB/Kelch-associated

No pathways found.

No diseases found.

Tissue Cell Type

bronchus

respiratory epithelial cells

esophagus

squamous epithelial cells

kidney

cells in tubules

pancreas

exocrine glandular cells

placenta

decidual cells

placenta

trophoblastic cells

salivary gland

glandular cells

small intestine

glandular cells

thyroid gland

glandular cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

TMPO

7112

P42166

0.62

ALOX12B

242

O75342

0.63

XIAP

331

P98170

0.63

CALML3

810

P27482

0.63

DSC2

1824

Q02487

0.63

TYMP

1890

P19971

0.63

ECM1

1893

Q16610

0.63

FLG

2312

P20930

0.63

GM2A

2760

P17900

0.63

HAL

3034

P42357

0.63

IVL

3713

P07476

0.63

JUP

3728

P14923

0.63

SERPINB13

5275

Q9UIV8

0.63

KLK7

5650

P49862

0.63

KLK10

5655

O43240

0.63

SULT2B1

6820

O00204

0.63

TGM1

7051

P22735

0.63

CPA4

51200

Q9UI42

0.63

S100A14

57402

Q9HCY8

0.63

MPPE1

65258

Q53F39

0.63

PLBD1

79887

Q6P4A8

0.63

POF1B

79983

Q8WVV4

0.63

APOL6

80830

Q9BWW8

0.63

FAM167A

83648

Q96KS9

0.63

CAPNS2

84290

Q96L46

0.63

PARD6B

84612

Q9BYG5

0.63

IL17F

112744

Q96PD4

0.63

CIB3

117286

Q96Q77

0.63

FRMD6

122786

Q96NE9

0.63

HYKK

123688

A2RU49

0.63

SNX20

124460

Q7Z614

0.63

A2ML1

144568

A8K2U0

0.63

SERPINA12

145264

Q8IW75

0.63

XAGE3

170626

Q8WTP9

0.63

APLF

200558

Q8IW19

0.63

FOXR1

283150

Q6PIV2

0.63

C5orf60

285679

A6NFR6

0.63

SBSN

374897

Q6UWP8

0.63

SUMO1P1

391257

N/A

0.63

GAGE12B; GAGE12C; GAGE12D; GAGE12E

100132399

A1L429

0.63

TSG101

7251

Q99816

0.70

GMCL1

64395

Q96IK5

0.70

EMD

2010

P50402

0.79

BYSL

705

Q13895

0.63

C21orf2

755

O43822

0.63

CLK2

1196

P49760

0.63

ELAVL1

1994

Q15717

0.63

FKBP1B

2281

P68106

0.63

FOSL2

2355

P15408

0.63

GAGE1

2543

Q13065

0.63

KIFC3

3801

Q9BVG8

0.63

KPNA2

3838

P52292

0.63

MID1

4281

O15344

0.63

MTRR

4552

Q9UBK8

0.63

NUMA1

4926

Q14980

0.63

PAX4

5078

O43316

0.63

PTPN7

5778

P35236

0.63

STK3

6788

Q13188

0.63

TCEB3

6924

Q14241

0.63

SUMO1

7341

P63165

0.63

XAGE2

9502

Q96GT9

0.63

TSSC4

10078

Q9Y5U2

0.63

KCNRG

10206

Q8N5I3

0.63

TRIM38

10475

O00635

0.63

KAT5

10524

Q92993

0.63

NEBL

10529

O76041

0.63

GLRX3

10539

O76003

0.63

MORF4L1

10933

Q9UBU8

0.63

MID2

11043

Q9UJV3

0.63

RAD54B

25788

Q9Y620

0.63

CHIC2

26511

Q9UKJ5

0.63

GAGE2E

26749

Q4V326

0.63

SLC15A3

51296

Q8IY34

0.63

MBIP

51562

Q9NS73

0.63

SYT17

51760

Q9BSW7

0.63

QRICH1

54870

Q2TAL8

0.63

PARP16

54956

Q8N5Y8

0.63

SHQ1

55164

Q6PI26

0.63

CCDC25

55246

Q86WR0

0.63

FAM63A

55793

Q8N5J2

0.63

TRIM54

57159

Q9BYV2

0.63

GRAMD1A

57655

Q96CP6

0.63

ZNF250

58500

P15622

0.63

SUCO

51430

Q9UBS9

0.72

GAGE5

2576

Q13069

0.73

PBXIP1

57326

Q96AQ6

0.73

GMCL1P1

64396

Q8NEA9

0.73

CUL3

8452

Q13618

0.82

GAGE12G

26748

P0CL81

0.82