Protein Description

Gene Symbol RHBDF1
Entrez ID 64285
Uniprot ID Q96CC6
Description rhomboid 5 homolog 1 (Drosophila)
Chromosomal Location chr16: 58,059-76,355
Ontology GO ID GO Term Definition Evidence

BP

GO:0008283

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

IMP

BP

GO:0015031

protein transport

The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

IEA

BP

GO:0016477

cell migration

The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.

IMP

BP

GO:0042058

regulation of epidermal growth factor receptor signaling pathway

Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.

IMP

BP

GO:0050708

regulation of protein secretion

Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.

IMP

BP

GO:0050709

negative regulation of protein secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.

IDA

BP

GO:0061136

regulation of proteasomal protein catabolic process

Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.

IDA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IDA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IDA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

MF

GO:0019838

growth factor binding

Interacting selectively and non-covalently with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.

IEA

Domain ID Description

IPR002610

Peptidase S54, rhomboid

IPR022241

Rhomboid serine protease

IPR022764

Peptidase S54, rhomboid domain

No pathways found.

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

TGFA

7039

P01135

0.55

MAPK14

1432

Q16539

0.63

SHMT2

6472

P34897

0.63