Gene Symbol | XYLT2 |
Entrez ID | 64132 |
Uniprot ID | Q9H1B5 |
Description | xylosyltransferase II |
Chromosomal Location | chr17: 50,346,092-50,363,138 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006024 |
glycosaminoglycan biosynthetic process |
The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars. |
NAS |
BP |
GO:0015012 |
heparan sulfate proteoglycan biosynthetic process |
The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. |
IEA|IMP |
BP |
GO:0030206 |
chondroitin sulfate biosynthetic process |
The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. |
IEA |
BP |
GO:0030210 |
heparin biosynthetic process |
The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. |
IEA |
BP |
GO:0050650 |
chondroitin sulfate proteoglycan biosynthetic process |
The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. |
IMP |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
IEA |
CC |
GO:0005575 |
cellular_component |
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together. |
ND |
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
IEA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
MF |
GO:0008375 |
acetylglucosaminyltransferase activity |
Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar. |
IEA |
MF |
GO:0030158 |
protein xylosyltransferase activity |
Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate. |
NAS |
Domain ID | Description |
---|---|
IPR003406 |
Glycosyl transferase, family 14 |
IPR024448 |
Xylosyltransferase |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00532 |
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate |
KEGG |
hsa00534 |
Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
UMLS CUI | UMLS Term |
---|---|
C0033847 |
Pseudoxanthoma Elasticum |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
IDS |
3423 |
P22304 |
0.63 |
TAZ |
6901 |
Q16635 |
0.63 |
CAMK1 |
8536 |
Q14012 |
0.63 |
B4GALT3 |
8703 |
O60512 |
0.63 |
CAMK1D |
57118 |
Q8IU85 |
0.63 |
POMK |
84197 |
Q9H5K3 |
0.63 |
FAM134C |
162427 |
Q86VR2 |
0.63 |