Protein Description

Gene Symbol CLSTN2
Entrez ID 64084
Uniprot ID Q9H4D0
Description calsyntenin 2
Chromosomal Location chr3: 139,935,185-140,577,397
Ontology GO ID GO Term Definition Evidence

BP

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.

IEA

BP

GO:0050806

positive regulation of synaptic transmission

Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

IEA

BP

GO:0051965

positive regulation of synapse assembly

Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IEA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IEA

CC

GO:0009986

cell surface

The external part of the cell wall and/or plasma membrane.

IEA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0045211

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.

IEA

MF

GO:0005509

calcium ion binding

Interacting selectively and non-covalently with calcium ions (Ca2+).

IEA

Domain ID Description

IPR002126

Cadherin

IPR013320

Concanavalin A-like lectin/glucanase domain

IPR015919

Cadherin-like

IPR026914

Calsyntenin

No pathways found.

UMLS CUI UMLS Term

C0019829

Hodgkin Disease

C0023903

Liver Neoplasms

C0026769

Multiple Sclerosis

C0027092

Myopia

Tissue Cell Type

cerebellum

Purkinje cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

No partners found.