PCOSBase

Protein Description

Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0006397	mRNA processing	Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.	IEA
BP	GO:0010923	negative regulation of phosphatase activity	Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.	IDA
MF	GO:0000166	nucleotide binding	Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.	IEA
MF	GO:0005515	protein binding	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	IPI
MF	GO:0044822	poly(A) RNA binding	Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.	IDA
MF	GO:0046872	metal ion binding	Interacting selectively and non-covalently with any metal ion.	IEA

Domain ID	Description
IPR000504	RNA recognition motif domain
IPR000571	Zinc finger, CCCH-type
IPR002483	PWI domain

Tissue	Cell Type
adrenal gland	glandular cells
appendix	glandular cells
appendix	lymphoid tissue
breast	glandular cells
breast	myoepithelial cells
bronchus	respiratory epithelial cells
caudate	glial cells
cerebellum	cells in granular layer
cerebellum	cells in molecular layer
cerebellum	Purkinje cells
cerebral cortex	neuronal cells
cervix, uterine	glandular cells
cervix, uterine	squamous epithelial cells
colon	endothelial cells
colon	glandular cells
colon	peripheral nerve/ganglion
duodenum	glandular cells
endometrium	glandular cells
epididymis	glandular cells
esophagus	squamous epithelial cells
fallopian tube	glandular cells
gallbladder	glandular cells
kidney	cells in glomeruli
kidney	cells in tubules
lymph node	non-germinal center cells
oral mucosa	squamous epithelial cells
pancreas	exocrine glandular cells
pancreas	islets of Langerhans
parathyroid gland	glandular cells
placenta	trophoblastic cells
prostate	glandular cells
rectum	glandular cells
salivary gland	glandular cells
seminal vesicle	glandular cells
skeletal muscle	myocytes
skin	fibroblasts
skin	keratinocytes
skin	Langerhans
skin	melanocytes
skin	epidermal cells
small intestine	glandular cells
smooth muscle	smooth muscle cells
soft tissue	fibroblasts
soft tissue	peripheral nerve
soft tissue	chondrocytes
spleen	cells in red pulp
spleen	cells in white pulp
stomach	glandular cells
testis	cells in seminiferous ducts
testis	Leydig cells
thyroid gland	glandular cells
tonsil	germinal center cells
tonsil	non-germinal center cells
tonsil	squamous epithelial cells
urinary bladder	urothelial cells
vagina	squamous epithelial cells

Pubmed ID	Author	Year	Title
17148555	Wood et al.	2007	Molecular Abnormalities in Oocytes from Women with Polycystic Ovary Syndrome Revealed by Microarray Analysis
22951915	Haozi et al.	2012	Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol	Entrez ID	Uniprot ID	Score
CRCP	27297	O75575	0.49
GBF1	8729	Q92538	0.49
PRPF3	9129	O43395	0.49
RAB3GAP2	25782	Q9H2M9	0.49
PPP1CA	5499	P62136	0.56
HNRNPA1	3178	P09651	0.63
NTRK1	4914	P04629	0.63
RPA1	6117	P27694	0.63
RPA2	6118	P15927	0.63
RPA3	6119	P35244	0.63
ATXN1	6310	P54253	0.63
STX5	6811	Q13190	0.63
XPO1	7514	O14980	0.63
NCK2	8440	O43639	0.63
HINFP	25988	Q9BQA5	0.63
LYPD3	27076	O95274	0.63
LUC7L	55692	Q9NQ29	0.63
RNF26	79102	Q9BY78	0.63
WDFY2	115825	Q96P53	0.63
CTBP2	1488	P56545	0.72
MKNK2	2872	Q9HBH9	0.72
FOXK2	3607	Q01167	0.72
LLGL2	3993	Q6P1M3	0.72
PAX6	5080	P26367	0.72
MAPK3	5595	P27361	0.72
RB1	5925	P06400	0.72
VCL	7414	P18206	0.72
YWHAZ	7534	P63104	0.72
FZD1	8321	Q9UP38	0.72
IKBKG	8517	Q9Y6K9	0.72
VPS26A	9559	O75436	0.72
BAIAP2	10458	Q9UQB8	0.72
KIFAP3	22920	Q92845	0.72
SETD1B	23067	Q9UPS6	0.72
KIAA1107	23285	Q9UPP5	0.72
CCDC88A	55704	Q3V6T2	0.72
DNAJC11	55735	Q9NVH1	0.72
CERK	64781	Q8TCT0	0.72
KBTBD7	84078	Q8WVZ9	0.72
CEP170P1	645455	Q96L14	0.72
SUMO2	6613	P61956	0.73