Protein Description

Gene Symbol MRPL17
Entrez ID 63875
Uniprot ID Q9NRX2
Description mitochondrial ribosomal protein L17
Chromosomal Location chr11: 6,680,782-6,683,401
Ontology GO ID GO Term Definition Evidence

BP

GO:0000002

mitochondrial genome maintenance

The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.

IBA

BP

GO:0070125

mitochondrial translational elongation

The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.

TAS

BP

GO:0070126

mitochondrial translational termination

The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).

TAS

CC

GO:0005743

mitochondrial inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

TAS

CC

GO:0005762

mitochondrial large ribosomal subunit

The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).

IBA

MF

GO:0003735

structural constituent of ribosome

The action of a molecule that contributes to the structural integrity of the ribosome.

IBA

MF

GO:0019904

protein domain specific binding

Interacting selectively and non-covalently with a specific domain of a protein.

IPI

Domain ID Description

IPR000456

Ribosomal protein L17

Pathway ID Pathway Term Pathway Source

hsa03010

Ribosome

KEGG

No diseases found.

Tissue Cell Type

appendix

glandular cells

breast

glandular cells

colon

glandular cells

colon

peripheral nerve/ganglion

duodenum

glandular cells

endometrium

glandular cells

epididymis

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

kidney

cells in tubules

oral mucosa

squamous epithelial cells

pancreas

islets of Langerhans

parathyroid gland

glandular cells

rectum

glandular cells

salivary gland

glandular cells

seminal vesicle

glandular cells

small intestine

glandular cells

stomach

glandular cells

testis

cells in seminiferous ducts

testis

Leydig cells

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

17563058

Skov et al.

2007

Reduced Expression of Nuclear-Encoded Genes Involved in Mitochondrial Oxidative Metabolism in Skeletal Muscle of Insulin-Resistant Women With Polycystic Ovary Syndrome

Gene Symbol Entrez ID Uniprot ID Score

RPS23

6228

P62266

0.56

LYST

1130

Q99698

0.63

ILF2

3608

Q12905

0.49

ILF3

3609

Q12906

0.49

MPV17

4358

P39210

0.49

ABCC1

4363

P33527

0.49

SLC25A3

5250

Q00325

0.49

TUFM

7284

P49411

0.49

PHB2

11331

Q99623

0.49

MRPL18

29074

Q9H0U6

0.49

MRPL22

29093

Q9NWU5

0.49

MRPL37

51253

Q9BZE1

0.49

DDX28

55794

Q9NUL7

0.49

POLR3A

11128

O14802

0.56

MRPL3

11222

P09001

0.56

MRPL13

28998

Q9BYD1

0.56

MRPL2

51069

Q5T653

0.56

POLR3B

55703

Q9NW08

0.56

RPL13

6137

P26373

0.63

RPS8

6202

P62241

0.63

MRPL28

10573

Q13084

0.63

MRPS30

10884

Q9NP92

0.63

ZC3H3

23144

Q8IXZ2

0.63

MRPL39

54148

Q9NYK5

0.63

MRPL4

51073

Q9BYD3

0.70

HCCS

3052

P53701

0.72

ICT1

3396

Q14197

0.72

BAG6

7917

P46379

0.72

MRPL50

54534

Q8N5N7

0.72

MRPL1

65008

Q9BYD6

0.72

UBA5

79876

Q9GZZ9

0.72

MRPL47

57129

Q9HD33

0.73

MRPL9

65005

Q9BYD2

0.82