| Gene Symbol | FKBP10 |
| Entrez ID | 60681 |
| Uniprot ID | Q96AY3 |
| Description | FK506 binding protein 10 |
| Chromosomal Location | chr17: 41,812,680-41,823,217 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0000413 |
protein peptidyl-prolyl isomerization |
The modification of a protein by cis-trans isomerization of a proline residue. |
IEA |
|
BP |
GO:0061077 |
chaperone-mediated protein folding |
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone. |
IBA |
|
CC |
GO:0005788 |
endoplasmic reticulum lumen |
The volume enclosed by the membranes of the endoplasmic reticulum. |
IEA |
|
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
IBA |
|
MF |
GO:0003755 |
peptidyl-prolyl cis-trans isomerase activity |
Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). |
IBA |
|
MF |
GO:0005509 |
calcium ion binding |
Interacting selectively and non-covalently with calcium ions (Ca2+). |
IEA |
|
MF |
GO:0005528 |
FK506 binding |
Interacting selectively and non-covalently with the 23-membered macrolide lactone FK506. |
IBA |
| Domain ID | Description |
|---|---|
|
IPR001179 |
FKBP-type peptidyl-prolyl cis-trans isomerase domain |
|
IPR002048 |
EF-hand domain |
|
IPR011992 |
EF-hand domain pair |
|
IPR018247 |
EF-Hand 1, calcium-binding site |
|
IPR023566 |
Peptidyl-prolyl cis-trans isomerase, FKBP-type |
| Tissue | Cell Type |
|---|---|
|
placenta |
decidual cells |
|
soft tissue |
fibroblasts |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ELN |
2006 |
P15502 |
0.55 |
|
DDX5 |
1655 |
P17844 |
0.63 |
|
LPP |
4026 |
Q93052 |
0.63 |
|
PPP1R7 |
5510 |
Q15435 |
0.63 |
|
ZPR1 |
8882 |
O75312 |
0.63 |
|
ARPC4 |
10093 |
P59998 |
0.63 |
|
ACTR3 |
10096 |
P61158 |
0.63 |
|
TTLL12 |
23170 |
Q14166 |
0.63 |
|
HSPBP1 |
23640 |
Q9NZL4 |
0.63 |
|
PPME1 |
51400 |
Q9Y570 |
0.63 |
|
DNAAF5 |
54919 |
Q86Y56 |
0.63 |
|
NPLOC4 |
55666 |
Q8TAT6 |
0.63 |
|
P3H1 |
64175 |
Q32P28 |
0.63 |
|
EFL1 |
79631 |
Q7Z2Z2 |
0.63 |
|
ECE1 |
1889 |
P42892 |
0.49 |
|
COA7 |
65260 |
Q96BR5 |
0.49 |
|
TCTN1 |
79600 |
Q2MV58 |
0.49 |
|
FBXO6 |
26270 |
Q9NRD1 |
0.63 |
|
H2AFX |
3014 |
P16104 |
0.72 |
|
SLC2A4 |
6517 |
P14672 |
0.72 |
|
SLX1A |
548593 |
Q9BQ83 |
0.76 |