Protein Description

Gene Symbol AASDHPPT
Entrez ID 60496
Uniprot ID Q9NRN7
Description aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Chromosomal Location chr11: 106,075,501-106,098,710
Ontology GO ID GO Term Definition Evidence

BP

GO:0015939

pantothenate metabolic process

The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.

TAS

BP

GO:0019878

lysine biosynthetic process via aminoadipic acid

The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.

IBA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0008897

holo-[acyl-carrier-protein] synthase activity

Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.

IDA|TAS

Domain ID Description

IPR008278

4'-phosphopantetheinyl transferase superfamily

Pathway ID Pathway Term Pathway Source

hsa00770

Pantothenate and CoA biosynthesis

KEGG

No diseases found.

Tissue Cell Type

cerebral cortex

neuropil

testis

cells in seminiferous ducts

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

TRAPPC4

51399

Q9Y296

0.49

HNRNPH1

3187

P31943

0.63

PLCG1

5335

P19174

0.63

NOL3

8996

O60936

0.63

EHD1

10938

Q9H4M9

0.63

EHD4

30844

Q9H223

0.63

ZC3HC1

51530

Q86WB0

0.63

POTEI

653269

P0CG38

0.63

STIL

6491

Q15468

0.73

ADSS

159

P30520

0.49

HNRNPA1

3178

P09651

0.49

UBE2D2

7322

P62837

0.49

UMPS

7372

P11172

0.49

RAE1

8480

P78406

0.49

DAZAP1

26528

Q96EP5

0.49

MOV10L1

54456

Q9BXT6

0.49

CAPZA2

830

P47755

0.63

HLA-B

3106

P30480

0.63

JUN

3725

P05412

0.63

MOV10

4343

Q9HCE1

0.63

NTRK1

4914

P04629

0.63

SGTA

6449

O43765

0.63

SIAH1

6477

Q8IUQ4

0.63

TRIP13

9319

Q15645

0.63

ULK2

9706

Q8IYT8

0.63

EIF1B

10289

O60739

0.63

NXF1

10482

Q9UBU9

0.63

PAXIP1

22976

Q6ZW49

0.63

FBXO6

26270

Q9NRD1

0.63

SLX4

84464

Q8IY92

0.63

BABAM1

29086

Q9NWV8

0.72

MDFI

4188

Q99750

0.73

TRAF2

7186

Q12933

0.74

USP22

23326

Q9UPT9

0.89