| Gene Symbol | AASDHPPT |
| Entrez ID | 60496 |
| Uniprot ID | Q9NRN7 |
| Description | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
| Chromosomal Location | chr11: 106,075,501-106,098,710 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0015939 | pantothenate metabolic process |
The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. | TAS |
BP | GO:0019878 | lysine biosynthetic process via aminoadipic acid |
The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway. | IBA |
CC | GO:0005829 | cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. | TAS |
CC | GO:0070062 | extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. | IDA |
MF | GO:0000287 | magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. | IDA |
MF | GO:0005515 | protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). | IPI |
MF | GO:0008897 | holo-[acyl-carrier-protein] synthase activity |
Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form. | IDA|TAS |
| Domain ID | Description |
|---|---|
IPR008278 | 4'-phosphopantetheinyl transferase superfamily |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
hsa00770 | Pantothenate and CoA biosynthesis | KEGG |
| Tissue | Cell Type |
|---|---|
cerebral cortex | neuropil |
testis | cells in seminiferous ducts |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
TRAPPC4 | 51399 | Q9Y296 | 0.49 |
HNRNPH1 | 3187 | P31943 | 0.63 |
PLCG1 | 5335 | P19174 | 0.63 |
NOL3 | 8996 | O60936 | 0.63 |
EHD1 | 10938 | Q9H4M9 | 0.63 |
EHD4 | 30844 | Q9H223 | 0.63 |
ZC3HC1 | 51530 | Q86WB0 | 0.63 |
POTEI | 653269 | P0CG38 | 0.63 |
STIL | 6491 | Q15468 | 0.73 |
ADSS | 159 | P30520 | 0.49 |
HNRNPA1 | 3178 | P09651 | 0.49 |
UBE2D2 | 7322 | P62837 | 0.49 |
UMPS | 7372 | P11172 | 0.49 |
RAE1 | 8480 | P78406 | 0.49 |
DAZAP1 | 26528 | Q96EP5 | 0.49 |
MOV10L1 | 54456 | Q9BXT6 | 0.49 |
CAPZA2 | 830 | P47755 | 0.63 |
HLA-B | 3106 | P30480 | 0.63 |
JUN | 3725 | P05412 | 0.63 |
MOV10 | 4343 | Q9HCE1 | 0.63 |
NTRK1 | 4914 | P04629 | 0.63 |
SGTA | 6449 | O43765 | 0.63 |
SIAH1 | 6477 | Q8IUQ4 | 0.63 |
TRIP13 | 9319 | Q15645 | 0.63 |
ULK2 | 9706 | Q8IYT8 | 0.63 |
EIF1B | 10289 | O60739 | 0.63 |
NXF1 | 10482 | Q9UBU9 | 0.63 |
PAXIP1 | 22976 | Q6ZW49 | 0.63 |
FBXO6 | 26270 | Q9NRD1 | 0.63 |
SLX4 | 84464 | Q8IY92 | 0.63 |
BABAM1 | 29086 | Q9NWV8 | 0.72 |
MDFI | 4188 | Q99750 | 0.73 |
TRAF2 | 7186 | Q12933 | 0.74 |
USP22 | 23326 | Q9UPT9 | 0.89 |