| Gene Symbol | AASDHPPT |
| Entrez ID | 60496 |
| Uniprot ID | Q9NRN7 |
| Description | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
| Chromosomal Location | chr11: 106,075,501-106,098,710 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0015939 |
pantothenate metabolic process |
The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. |
TAS |
|
BP |
GO:0019878 |
lysine biosynthetic process via aminoadipic acid |
The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway. |
IBA |
|
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
|
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
|
MF |
GO:0000287 |
magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0008897 |
holo-[acyl-carrier-protein] synthase activity |
Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form. |
IDA|TAS |
| Domain ID | Description |
|---|---|
|
IPR008278 |
4'-phosphopantetheinyl transferase superfamily |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa00770 |
Pantothenate and CoA biosynthesis |
KEGG |
| Tissue | Cell Type |
|---|---|
|
cerebral cortex |
neuropil |
|
testis |
cells in seminiferous ducts |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
TRAPPC4 |
51399 |
Q9Y296 |
0.49 |
|
HNRNPH1 |
3187 |
P31943 |
0.63 |
|
PLCG1 |
5335 |
P19174 |
0.63 |
|
NOL3 |
8996 |
O60936 |
0.63 |
|
EHD1 |
10938 |
Q9H4M9 |
0.63 |
|
EHD4 |
30844 |
Q9H223 |
0.63 |
|
ZC3HC1 |
51530 |
Q86WB0 |
0.63 |
|
POTEI |
653269 |
P0CG38 |
0.63 |
|
STIL |
6491 |
Q15468 |
0.73 |
|
ADSS |
159 |
P30520 |
0.49 |
|
HNRNPA1 |
3178 |
P09651 |
0.49 |
|
UBE2D2 |
7322 |
P62837 |
0.49 |
|
UMPS |
7372 |
P11172 |
0.49 |
|
RAE1 |
8480 |
P78406 |
0.49 |
|
DAZAP1 |
26528 |
Q96EP5 |
0.49 |
|
MOV10L1 |
54456 |
Q9BXT6 |
0.49 |
|
CAPZA2 |
830 |
P47755 |
0.63 |
|
HLA-B |
3106 |
P30480 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
MOV10 |
4343 |
Q9HCE1 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
SGTA |
6449 |
O43765 |
0.63 |
|
SIAH1 |
6477 |
Q8IUQ4 |
0.63 |
|
TRIP13 |
9319 |
Q15645 |
0.63 |
|
ULK2 |
9706 |
Q8IYT8 |
0.63 |
|
EIF1B |
10289 |
O60739 |
0.63 |
|
NXF1 |
10482 |
Q9UBU9 |
0.63 |
|
PAXIP1 |
22976 |
Q6ZW49 |
0.63 |
|
FBXO6 |
26270 |
Q9NRD1 |
0.63 |
|
SLX4 |
84464 |
Q8IY92 |
0.63 |
|
BABAM1 |
29086 |
Q9NWV8 |
0.72 |
|
MDFI |
4188 |
Q99750 |
0.73 |
|
TRAF2 |
7186 |
Q12933 |
0.74 |
|
USP22 |
23326 |
Q9UPT9 |
0.89 |