BP

GO:0006766

vitamin metabolic process

The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.

TAS

BP

GO:0006805

xenobiotic metabolic process

The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.

IDA

BP

GO:0034653

retinoic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.

IDA

BP

GO:0042573

retinoic acid metabolic process

The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.

IDA

BP

GO:0048387

negative regulation of retinoic acid receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.

TAS

BP

GO:0055114

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

IEA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

TAS

CC

GO:0031090

organelle membrane

A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.

IEA

MF

GO:0001972

retinoic acid binding

Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.

IDA

MF

GO:0005506

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

IEA

MF

GO:0008401

retinoic acid 4-hydroxylase activity

Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.

IDA|TAS

MF

GO:0016709

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

IDA

MF

GO:0019825

oxygen binding

Interacting selectively and non-covalently with oxygen (O2).

TAS

MF

GO:0020037

heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

NAS