Protein Description

Gene Symbol CACNG6
Entrez ID 59285
Uniprot ID Q9BXT2
Description calcium channel, voltage-dependent, gamma subunit 6
Chromosomal Location chr19: 53,992,288-54,012,669
Ontology GO ID GO Term Definition Evidence

BP

GO:0006816

calcium ion transport

The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

NAS

BP

GO:0034765

regulation of ion transmembrane transport

Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.

IEA

BP

GO:0061337

cardiac conduction

Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.

TAS

BP

GO:0070588

calcium ion transmembrane transport

A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

IEA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

TAS

CC

GO:0005891

voltage-gated calcium channel complex

A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.

NAS

MF

GO:0005245

voltage-gated calcium channel activity

Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

NAS

Domain ID Description

IPR004031

PMP-22/EMP/MP20/Claudin superfamily

IPR008368

Voltage-dependent calcium channel, gamma subunit

IPR008370

Voltage-dependent calcium channel, gamma-6 subunit

Pathway ID Pathway Term Pathway Source

hsa04010

MAPK signaling pathway

KEGG

hsa04260

Cardiac muscle contraction

KEGG

hsa04261

Adrenergic signaling in cardiomyocytes

KEGG

hsa04921

Oxytocin signaling pathway

KEGG

hsa05410

Hypertrophic cardiomyopathy (HCM)

KEGG

hsa05412

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

KEGG

hsa05414

Dilated cardiomyopathy

KEGG

WP2118

Arrhythmogenic Right Ventricular Cardiomyopathy

WikiPathways

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

No partners found.