| Gene Symbol | WIZ |
| Entrez ID | 58525 |
| Uniprot ID | O95785 |
| Description | widely interspaced zinc finger motifs |
| Chromosomal Location | chr19: 15,419,980-15,449,951 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0010571 |
positive regulation of nuclear cell cycle DNA replication |
Any process that activates or increases the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. |
IMP |
|
BP |
GO:0050821 |
protein stabilization |
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation. |
IMP |
|
BP |
GO:0070208 |
protein heterotrimerization |
The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical. |
IDA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
|
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
|
MF |
GO:0070984 |
SET domain binding |
Interacting selectively and non-covalently with a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR013087 |
Zinc finger C2H2-type |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
bone marrow |
hematopoietic cells |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
endothelial cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
hippocampus |
glial cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
liver |
hepatocytes |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
pancreas |
exocrine glandular cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
soft tissue |
fibroblasts |
|
soft tissue |
adipocytes |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ZC3H4 |
23211 |
Q9UPT8 |
0.49 |
|
CTBP2 |
1488 |
P56545 |
0.63 |
|
RPP30 |
10556 |
P78346 |
0.63 |
|
PRPF31 |
26121 |
Q8WWY3 |
0.63 |
|
COPRS |
55352 |
Q9NQ92 |
0.63 |
|
BAP18 |
124944 |
Q8IXM2 |
0.63 |
|
UACA |
55075 |
Q9BZF9 |
0.72 |
|
MIER1 |
57708 |
Q8N108 |
0.72 |
|
POLR1E |
64425 |
Q9GZS1 |
0.72 |
|
WDR77 |
79084 |
Q9BQA1 |
0.72 |
|
USP45 |
85015 |
Q70EL2 |
0.72 |
|
CDYL2 |
124359 |
Q8N8U2 |
0.72 |
|
MIER3 |
166968 |
Q7Z3K6 |
0.72 |
|
CTBP1 |
1487 |
Q13363 |
0.74 |
|
EHMT1 |
79813 |
Q9H9B1 |
0.84 |
|
EHMT2 |
10919 |
Q96KQ7 |
0.88 |
|
EWSR1 |
2130 |
Q01844 |
0.49 |
|
BRCA1 |
672 |
P38398 |
0.63 |
|
CDKN1A |
1026 |
P38936 |
0.63 |
|
RCC1 |
1104 |
P18754 |
0.63 |
|
CTSG |
1511 |
P08311 |
0.63 |
|
NOTCH1 |
4851 |
P46531 |
0.63 |
|
PIN1 |
5300 |
Q13526 |
0.63 |
|
RNF2 |
6045 |
Q99496 |
0.63 |
|
RPS9 |
6203 |
P46781 |
0.63 |
|
RPS10 |
6204 |
P46783 |
0.63 |
|
SUMO2 |
6613 |
P61956 |
0.63 |
|
TFAP4 |
7023 |
Q01664 |
0.63 |
|
TK1 |
7083 |
P04183 |
0.63 |
|
EED |
8726 |
O75530 |
0.63 |
|
TSC22D1 |
8848 |
Q15714 |
0.63 |
|
TRIM10 |
10107 |
Q9UDY6 |
0.63 |
|
RPP14 |
11102 |
O95059 |
0.63 |
|
ZBTB1 |
22890 |
Q9Y2K1 |
0.63 |
|
SNW1 |
22938 |
Q13573 |
0.63 |
|
FBXW11 |
23291 |
Q9UKB1 |
0.63 |
|
MIER2 |
54531 |
Q8N344 |
0.63 |
|
OSGEP |
55644 |
Q9NPF4 |
0.63 |
|
DOK5 |
55816 |
Q9P104 |
0.63 |
|
SMARCAD1 |
56916 |
Q9H4L7 |
0.63 |
|
HECW2 |
57520 |
Q9P2P5 |
0.63 |
|
C8orf33 |
65265 |
Q9H7E9 |
0.63 |
|
BIRC7 |
79444 |
Q96CA5 |
0.63 |
|
ZBTB46 |
140685 |
Q86UZ6 |
0.63 |
|
RICTOR |
253260 |
Q6R327 |
0.63 |
|
SMN1; SMN2 |
6606 |
Q16637 |
0.63 |
|
APC |
324 |
P25054 |
0.72 |
|
FOXG1 |
2290 |
P55316 |
0.72 |
|
FOXE1 |
2304 |
O00358 |
0.72 |
|
HDAC2 |
3066 |
Q92769 |
0.72 |
|
MAX |
4149 |
P61244 |
0.72 |
|
SUV39H1 |
6839 |
O43463 |
0.72 |
|
TUBG1 |
7283 |
P23258 |
0.72 |
|
CBX4 |
8535 |
O00257 |
0.72 |
|
CBX5 |
23468 |
P45973 |
0.72 |
|
SUV39H2 |
79723 |
Q9H5I1 |
0.72 |
|
ZNF644 |
84146 |
Q9H582 |
0.72 |
|
SUMO1 |
7341 |
P63165 |
0.73 |
|
CDYL |
9425 |
Q9Y232 |
0.82 |