Protein Description

Gene Symbol PLEKHB1
Entrez ID 58473
Uniprot ID Q9UF11
Description pleckstrin homology domain containing B1
Chromosomal Location chr11: 73,646,178-73,662,819
Ontology GO ID GO Term Definition Evidence

BP

GO:0007275

multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

IEA

BP

GO:0007602

phototransduction

The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.

NAS

BP

GO:0045595

regulation of cell differentiation

Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.

IBA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IEA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IDA

MF

GO:0004871

signal transducer activity

Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.

TAS

MF

GO:0008022

protein C-terminus binding

Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.

IEA

MF

GO:0042803

protein homodimerization activity

Interacting selectively and non-covalently with an identical protein to form a homodimer.

IEA

Domain ID Description

IPR001849

Pleckstrin homology domain

IPR011993

PH domain-like

No pathways found.

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

GNGT1

2792

P63211

0.52

SMAD1

4086

Q15797

0.59

TGFBR1

7046

P36897

0.59

ATXN1

6310

P54253

0.63

PLEKHH2

130271

Q8IVE3

0.63

SH2D2A

9047

Q9NP31

0.72

GNAS

2778

P84996

0.49

ACVR1

90

Q04771

0.59

BMPR1B

658

O00238

0.59

RAP1GDS1

5910

P52306

0.63

RBFOX2

23543

O43251

0.63

ZDHHC17

23390

Q8IUH5

0.72