BP

GO:0001558

regulation of cell growth

Any process that modulates the frequency, rate, extent or direction of cell growth.

IBA

BP

GO:0010951

negative regulation of endopeptidase activity

Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.

IEA

BP

GO:0030308

negative regulation of cell growth

Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.

NAS

BP

GO:0032355

response to estradiol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.

IEA

BP

GO:0042493

response to drug

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.

IEA

BP

GO:0050680

negative regulation of epithelial cell proliferation

Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.

IEA

BP

GO:0050728

negative regulation of inflammatory response

Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.

IEA

BP

GO:0061045

negative regulation of wound healing

Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.

IEA

CC

GO:0005615

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

IBA|NAS

MF

GO:0003674

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

ND

MF

GO:0004867

serine-type endopeptidase inhibitor activity

Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.

IEA