Protein Description

Gene Symbol ARHGAP20
Entrez ID 57569
Uniprot ID Q9P2F6
Description Rho GTPase activating protein 20
Chromosomal Location chr11: 110,577,042-110,713,189
Ontology GO ID GO Term Definition Evidence

BP

GO:0007165

signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

IEA

BP

GO:0043547

positive regulation of GTPase activity

Any process that activates or increases the activity of a GTPase.

IEA

BP

GO:0051056

regulation of small GTPase mediated signal transduction

Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.

TAS

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

MF

GO:0005096

GTPase activator activity

Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

TAS

Domain ID Description

IPR000159

Ras-associating (RA) domain

IPR000198

Rho GTPase-activating protein domain

IPR001849

Pleckstrin homology domain

IPR008936

Rho GTPase activation protein

IPR011993

PH domain-like

IPR029071

Ubiquitin-related domain

No pathways found.

UMLS CUI UMLS Term

C0002395

Alzheimer'S Disease

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

GRB2

2885

P62993

0.63

TERF2

7014

Q15554

0.63